Evidence map›Paper›PMID 40861574›Full record

ReviewCureus2025

Evolving Surgical Approaches in the Management of Pancreatic Masses: From Open Resection to Minimally Invasive and Robotic Techniques.

Cara Mohammed, Patricio Xavier Duran S, Hugh Kolomar, Tanmay Thirth, Simcha Bulmash, Sharvari Vikram Joshi, Tannia Payan Serrano, Greeshma Reddy, Turimula Arpan, Deepika Palegar Thuli and 2 more

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cara MohammedOrthopaedic Surgery, Sangre Grande Hospital, Sangre Grande, TTO.
Patricio Xavier Duran SInternal Medicine, Universidad de Cuenca, Cuenca, ECU.
Hugh KolomarInternal Medicine, Niš Clinical Centre, Niš, SRB.
Tanmay ThirthSurgery, St. Philomena's Hospital, Bengaluru, IND.
Simcha BulmashSurgery, Technion-Israel Institute of Technology, The Ruth and Bruce Rappaport Faculty of Medicine, Haifa, ISR.
Sharvari Vikram JoshiSurgery, Goa Medical College and Hospital, Bambolim, IND.
Tannia Payan SerranoSurgery, Hospital General de Occidente, Universidad de Guadalajara, Jalisco, MEX.
Greeshma ReddySurgery, Sakra World Hospital, Bengaluru, IND.
Turimula ArpanMedicine, Sree Venkateswaraa Medical College and Hospital, Mahabubnagar, IND.
Deepika Palegar ThuliSurgery, Osmania Medical College, Hyderabad, IND.
Areehah Zafar MasoodSurgery, Ziauddin Medical College, Karachi, PAK.
Manju RaiBiotechnology, Shri Venkateshwara University, Amroha, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic masses represent a heterogeneous spectrum of neoplasms, ranging from benign lesions such as serous cystadenomas to malignant tumors such as pancreatic ductal adenocarcinoma (PDAC). Timely and accurate differentiation among these entities is essential for devising effective therapeutic strategies. Recent advancements in diagnostic modalities, surgical techniques, and perioperative care have significantly influenced the management of pancreatic masses. This narrative review synthesizes current literature and clinical practices related to the surgical management of pancreatic masses. It examines the evolution of diagnostic tools, operative approaches, perioperative management, and the integration of emerging technologies in clinical decision-making. Imaging modalities such as contrast-enhanced CT, MRI, and endoscopic ultrasound have improved the precision of diagnosis and staging. Histopathological confirmation remains the gold standard for definitive diagnosis. Surgical options, including partial and total pancreatectomy, are tailored according to tumor type and stage, with resection being the only curative treatment for PDAC. Minimally invasive approaches, such as laparoscopic and robotic-assisted surgeries, offer the benefits of reduced morbidity and faster recovery while maintaining oncological outcomes. Neoadjuvant therapy shows promise in enhancing surgical success and survival in resectable and borderline resectable tumors. Postoperative complications such as pancreatic fistulas, delayed gastric emptying, and endocrine/exocrine insufficiencies are common challenges. For non-resectable tumors, palliative options such as biliary bypass and endoscopic stenting focus on symptom relief and quality of life. The surgical management of pancreatic masses has evolved significantly, driven by advancements in diagnostics, minimally invasive techniques, and supportive perioperative care. Emerging tools such as intraoperative imaging, artificial intelligence, and precision medicine are enabling more personalized treatment plans. A multidisciplinary approach remains critical in optimizing outcomes for patients with pancreatic neoplasms.

Indexed as

biliary bypassendoscopic ultrasoundminimally invasive surgerymultidisciplinary approachneoadjuvant therapypancreatic ductal adenocarcinomapancreatic massespancreatic resectionpostoperative complicationsrobotic-assisted surgery

Identifiers

PMID40861574
PMCPMC12373263

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.