ArticleAdvanced biomedical research2025
The Efficacy of Focused Extracorporeal Shockwave Therapy for the Knee Osteoarthritis: A Clinical Trial Study.
Article in Advanced biomedical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Extracorporeal shockwave therapy in tissue repair and regeneration.Wiener medizinische Wochenschrift (1946) · 2026Review
- [Soft tissue engineering in orthopedics : Regenerative synergistic effects of shockwave therapy, PRP, EMTT, and hyaluronic acid].Orthopadie (Heidelberg, Germany) · 2026Review
- Extracorporeal Shock Wave Therapy in Knee Osteoarthritis: A Mechanistic Narrative Review of Neurogenic Inflammation and the MMP/ADAMTS Axis.International journal of general medicine · 2026Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Osteoarthritis is the most common form of degenerative arthritis. To date, varieties of management approaches have been recommended for osteoarthritis, but their outcomes are not consistent. In the current study, it is aimed to assess the efficacy of focused shockwave therapy for the treatment of knee osteoarthritis. Materials and Methods: The current randomized clinical trial was conducted on 42 patients (22 cases and 20 controls, with mean age of 58.02 ± 9.90 years) with knee osteoarthritis in 2018-2019, in Isfahan, Iran. Both groups received topical analgesic plus hot pack and celecoxib 200 mg 14d. The cases underwent shockwave therapy, whereas the controls underwent sham shockwave therapy. Pain score based on visual analog scale (VAS), Knee injury and Outcome Osteoarthritis Score (KOOS) and Roles and Maudsley scores were assessed basically and within 12 weeks. Results: Disease-related symptoms (as a part of KOOS questionnaire) improved following the interventions in both groups ( Conclusion: We found that focused shockwave use can appropriately rehabilitate the knee function and reduce knee osteoarthritis pain. Further studies to assess the best dose and the best location of shockwave administration are strongly recommended.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.