Evidence map›Paper›PMID 40863386›Full record

ReviewJournal of cardiovascular development and disease2025

Multimodality Imaging in Eosinophilic Myocarditis: A Rare Cause of Heart Failure.

Vincenzo Viccaro, Amabile Valotta, Elena Checcoli, Susanna Landi, Fabio Cattaneo, Andrea Milzi, Mattia Duchini, Giacomo Maria Viani, Alessandro Caretta, Susanne Schlossbauer and 6 more

Abstract readReview
In one paragraph

Review in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Vincenzo ViccaroDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.ORCID 0009-0009-1156-6572
Amabile ValottaDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.ORCID 0000-0002-9329-4874
Elena CheccoliDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.
Susanna LandiDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.
Fabio CattaneoDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.ORCID 0000-0003-3719-8180
Andrea MilziDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.ORCID 0000-0001-7580-8029
Mattia DuchiniDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.
Giacomo Maria VianiDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.
Alessandro CarettaDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.
Susanne SchlossbauerDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.
Antonio LandiDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.ORCID 0000-0002-0412-1083
Laura Anna LeoDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.ORCID 0000-0002-2652-5927
Giorgio TregliaFaculty of Biomedical Sciences, Università Della Svizzera Italiana, 6900 Lugano, Switzerland.ORCID 0000-0001-9808-780X
Giovanni PedrazziniDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.ORCID 0000-0002-6513-3985
Marco ValgimigliDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.
Anna Giulia PavonDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophilic myocarditis (EM) is a rare and potentially fatal form of acute myocarditis. Currently, no validated diagnostic criteria exist, and definitive diagnosis relies on endomyocardial biopsy (EMB) not devoid of periprocedural complications. This review aims to explore how a multimodality imaging approach can support early diagnosis, reduce reliance on EMB, enable risk stratification and monitor the response to anti-inflammatory therapy. In particular, while echocardiography provides rapid and useful information in suspected EM, cardiac magnetic resonance (CMR) remains the non-invasive gold standard for diagnosis due to its ability to provide accurate tissue characterization. Moreover, positron emission tomography/computed tomography (PET/CT) and cardiac CT (CCT) may offer valuable insights, particularly when echocardiographic image quality is poor or CMR is contraindicated or unavailable. Based on our experience and current literature, an optimal multimodality imaging approach should reserve EMB only for high-risk or inconclusive cases. Furthermore, this strategy offers complementary information, supporting clinical decisions and optimizing long-term outcomes.

Indexed as

acute heart failurecardiac magnetic resonancecardiogenic shockeosinophilic myocarditiseosinophilic syndromemultimodality imaging

Identifiers

PMID40863386
PMCPMC12386955

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.