Evidence mapPaperPMID 40863945Full record

ArticleToxics2025

The TyG Index Mediates Air-Pollution-Associated Chronic Kidney Disease Incidence in HIV/AIDS Patients: A 20-Year Cohort Study.

Xiaoxia Liu, Xiuli Zhao, Lu Ye, Chengfeng Hu, Zhihao Xie, Jianan Ma, Xia Wang, Wei Liang

Abstract read
In one paragraph

Article in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoxia LiuZhenjiang Center for Disease Control and Prevention, 9# South Huangshan Road, Zhenjiang 212002, China.
Xiuli ZhaoSchool of Public Health, Faculty of Medicine, Yangzhou University, 136# Jiangyang Middle Road, Yangzhou 225000, China.
Lu YeZhenjiang Center for Disease Control and Prevention, 9# South Huangshan Road, Zhenjiang 212002, China.
Chengfeng HuZhenjiang Center for Disease Control and Prevention, 9# South Huangshan Road, Zhenjiang 212002, China.
Zhihao XieSchool of Public Health, Faculty of Medicine, Yangzhou University, 136# Jiangyang Middle Road, Yangzhou 225000, China.
Jianan MaSchool of Public Health, Faculty of Medicine, Yangzhou University, 136# Jiangyang Middle Road, Yangzhou 225000, China.
Xia WangWuhan Center for Disease Control and Prevention, 288# Machang Road, Wuhan 430024, China.ORCID 0000-0002-5128-9380
Wei LiangSchool of Public Health, Faculty of Medicine, Yangzhou University, 136# Jiangyang Middle Road, Yangzhou 225000, China.ORCID 0000-0002-4725-9605

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ambient air pollutants (APs) are associated with increased chronic kidney disease (CKD) risk in general populations, but their renal impact on HIV/AIDS patients remains understudied. This dynamic cohort included 7981 HIV/AIDS patients without baseline kidney disease from Wuhan and Zhenjiang, followed every 6 months with fasting blood tests to assess the triglyceride-glucose (TyG) index and estimated glomerular filtration rate (eGFR). Monthly average exposures to six APs were estimated from geocoded residential addresses. Modified Poisson regression models were used to assess associations between cumulative AP exposure and CKD incidence, with mediation analysis conducted to explore the potential role of the TyG index. Weighted quantile sum regression was applied to evaluate the joint effects of six APs. During the follow-up period, 168 new cases of CKD were identified. Each interquartile range increase in PM

Indexed as

air pollutantschronic kidney diseaseeGFRHIV/AIDSTyG

Identifiers

PMID40863945
PMCPMC12389780

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.