Evidence map›Paper›PMID 40864056›Full record

ArticleToxins2025

A New Kv1.3 Channel Blocker from the Venom of the Ant

Guillaume Boy, Laurence Jouvensal, Nathan Téné, Jean-Luc Carayon, Elsa Bonnafé, Françoise Paquet, Michel Treilhou, Karine Loth, Arnaud Billet

Abstract read
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guillaume BoyEquipe BTSB EA-7417, Institut National Universitaire Champollion, Place de Verdun, 81012 Albi, France.ORCID 0009-0009-9630-9937
Laurence JouvensalCentre de Biophysique Moléculaire, Centre National de la Recherche Scientifique (CNRS), Unité Propre de Recherche (UPR) 4301, 45071 Orléans, France.ORCID 0000-0001-9223-9286
Nathan TénéEquipe BTSB EA-7417, Institut National Universitaire Champollion, Place de Verdun, 81012 Albi, France.ORCID 0000-0003-3958-8182
Jean-Luc CarayonEquipe BTSB EA-7417, Institut National Universitaire Champollion, Place de Verdun, 81012 Albi, France.
Elsa BonnaféEquipe BTSB EA-7417, Institut National Universitaire Champollion, Place de Verdun, 81012 Albi, France.ORCID 0000-0002-2630-4876
Françoise PaquetCentre de Biophysique Moléculaire, Centre National de la Recherche Scientifique (CNRS), Unité Propre de Recherche (UPR) 4301, 45071 Orléans, France.ORCID 0000-0001-8838-3445
Michel TreilhouEquipe BTSB EA-7417, Institut National Universitaire Champollion, Place de Verdun, 81012 Albi, France.
Karine LothCentre de Biophysique Moléculaire, Centre National de la Recherche Scientifique (CNRS), Unité Propre de Recherche (UPR) 4301, 45071 Orléans, France.ORCID 0000-0001-7058-8661
Arnaud BilletEquipe BTSB EA-7417, Institut National Universitaire Champollion, Place de Verdun, 81012 Albi, France.ORCID 0000-0002-9738-7330

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ant venoms are rich sources of bioactive molecules, including peptide toxins with potent and selective activity on ion channels, which makes them valuable for pharmacological research and therapeutic development. Voltage-dependent potassium (Kv) channels, critical for regulating cellular excitability or cell cycle progression control, are targeted by a diverse array of venom-derived peptides. This study focuses on MYRTX

Indexed as

AntsAnt VenomsKv1.3 Potassium ChannelPeptidesPotassium Channel BlockersAnimalsCell SurvivalHEK293 CellsHumansAnt VenomsKv1.3 Potassium ChannelPeptidesPotassium Channel Blockersant venom peptidefunctional dyadKv channels

Identifiers

PMID40864056
PMCPMC12389897

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.