Evidence map›Paper›PMID 40864894›Full record

ArticleJournal of medical Internet research2025

The Effectiveness of Nurse-Led Multidimensional Digital Cardiac Rehabilitation in Patients With Unstable Angina Undergoing Percutaneous Coronary Intervention: Emulated Target Trial.

Tong Zhou, Yijun Wang, Jun Wang, Jinjun Liu, Nana Zhang, Xiaoling Zhang, Shengnan Yao, Mingming Tang, Guixia Xu, Yongxia Chen

Abstract read
In one paragraph

Article in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. A multi-layer retrieval-augmented large language model framework for enhancing hypertension education.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tong Zhou *Department of Cardiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.ORCID http://orcid.org/0000-0002-7139-5594
Yijun Wang *Department of Cardiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.ORCID http://orcid.org/0009-0001-2972-8367
Jun Wang *Department of Cardiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.ORCID http://orcid.org/0009-0007-1477-9093
Jinjun Liu *Department of Cardiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.ORCID http://orcid.org/0009-0009-1799-2708
Nana ZhangDepartment of Cardiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.ORCID http://orcid.org/0009-0000-4739-3612
Xiaoling ZhangDepartment of Cardiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.ORCID http://orcid.org/0009-0007-9120-1949
Shengnan YaoDepartment of Cardiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.ORCID http://orcid.org/0009-0004-2115-8031
Mingming TangDepartment of Cardiology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, China.ORCID http://orcid.org/0009-0000-5101-0645
Guixia Xu *Department of Nursing, The First Affiliated Hospital of Bengbu Medical University, No. 287, Changhuai Road, Longzihu District, Bengbu, 233000, China, 86 05523086107.ORCID http://orcid.org/0009-0002-9919-6826
Yongxia Chen *Department of Nursing, The First Affiliated Hospital of Bengbu Medical University, No. 287, Changhuai Road, Longzihu District, Bengbu, 233000, China, 86 05523086107.ORCID http://orcid.org/0009-0003-0744-8721

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiac rehabilitation (CR) interventions for patients with coronary heart disease are increasingly adopted. However, research on the integration of digital health technologies into CR for patients with unstable angina (UA) undergoing percutaneous coronary intervention (PCI) remains limited. Objective: This study assessed the effectiveness of a multidimensional digital CR program for patients with UA undergoing PCI. Methods: This prospective study enrolled 164 patients with UA who underwent PCI between April and June 2022. Patients were assigned to either the usual care group (April-May 2022) or the multidimensional digital CR intervention group (May-June 2022). The intervention group received rehabilitation through a nurse-led, multidisciplinary team, using a customized digital CR program. This program encompassed 7 key rehabilitation components: exercise, medication management, nutritional guidance, psychological support, sleep management, health education, and smoking cessation assistance. The usual care group received standardized treatment and routine nursing care. To minimize selection bias, propensity score matching was applied between the 2 groups. The primary outcomes included changes in the 6-minute walk test (6MWT), 12-item Short Form Health Survey (SF-12) scores, and frailty phenotype scores at 3 months. Secondary outcomes assessed differences in gait speed, 30-second chair stand test (30-s CST), grip strength, waist circumference (WC), BMI, and lipid profiles at 3 months. Results: A total of 136 patients were included in the final analysis. At 3 months, the intervention group demonstrated significant improvements in frailty status compared to the control group. The proportion of prefrail patients decreased from 100% (68 patients) to 75% (51 patients), while nonfrail patients increased from 0% to 25% (17 patients; P<.001). Regarding physical fitness, the intervention group exhibited improvements in 6MWT: from 347.06 (SD 32.43) to 375.22 (SD 29.71) m (P<.001); gait speed: from 0.87 (SD 0.17) to 1.05 (SD 0.14) m/s (P<.001); and 30-s CST: from 10.0 (SD 1.89) to 12.71 (SD 1.97; P<.001). Grip strength, BMI, and WC improved significantly in the intervention group. Grip strength increased from 16.64 (SD 6.57) to 20.74 (SD 5.37; P<.001). BMI decreased from 25.74 (SD 3.05) to 23.88 (SD 2.14; P<.001), and WC decreased from 94.98 (SD 7.87) to 89.91 (SD 7.50) cm (P<.001). The intervention group achieved greater improvements in lipid profiles, with significant reductions in total cholesterol (P<.001), triglycerides (P<.001), and low-density lipoprotein cholesterol (P<.001), while high-density lipoprotein cholesterol remained stable (P=.45). Conclusions: This study demonstrates that a novel multidimensional digital CR program is acceptable and effective in improving functional status and health-related quality of life in patients with UA undergoing PCI within a short timeframe.

Indexed as

Angina, UnstableCardiac RehabilitationPercutaneous Coronary InterventionAgedFemaleHumansMaleMiddle AgedProspective StudiesBaduanjincardiac rehabilitationdigital health technologiesmHealthmulticomponent interventionmultidimensional interventionpercutaneous coronary interventionunstable angina

Identifiers

PMID40864894
PMCPMC12384693

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.