ArticleThe Journal of nutrition2025
Fish Intake and Polyunsaturated Fatty Acids in Relation to Colorectal Cancer Risk in the Black Women's Health Study.
Article in The Journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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5 authors.
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Abstract
backgroundBlack Americans have the highest colorectal cancer (CRC) incidence and mortality rates of any racial/ethnic group in the United States. Diets high in fish consumption and long-chain n-3 (ω-3) polyunsaturated fatty acids (PUFAs) have been associated with reduced risk of CRC. Black Americans have higher overall fish consumption than White Americans but are more likely to consume fish that are lower in n-3 PUFAs.
objectivesWe prospectively assessed fish intake and PUFAs in relation to risk of CRC, using data from the Black Women's Health Study (1995-2021).
methodsDietary data were collected from validated food frequency questionnaires completed by participants in 1995 and 2001. Cox-proportional hazards regression models were utilized to estimate multivariable-adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between fish/PUFA intake and incident CRC. Models were adjusted for total caloric intake, fruit/vegetable intake, and red meat intake, among other factors.
resultsAmong 52,690 Black women aged 21-69 y at baseline, 687 women developed incident CRC over 24 y of follow-up. High intake of baked fish (>8.09 g/1000 kcal), compared with low intake (<0.38 g/1000 kcal), was associated with a 26% reduced risk of incident CRC (HR
conclusionsWe found that high intake of baked fish was associated with a decreased CRC risk. This finding suggests that increasing baked fish intake could be a valuable strategy for CRC prevention among Black women.
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