Evidence map›Paper›PMID 40866739›Full record

ReviewJournal of assisted reproduction and genetics2025

Advances in supplementation strategies for enhancing bovine in vitro embryo production: a review of growth factors and antioxidants.

Onalenna Kereilwe

Abstract readReview
In one paragraph

Review in Journal of assisted reproduction and genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Impact of Nutrition on Embryo Production in Cattle: Mechanistic Insights.Animals : an open access journal from MDPI · 2026
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Onalenna KereilweDepartment of Animal Science, Botswana University of Agriculture and Natural Resources, Gaborone, Southern, Botswana. onalennaker@yahoo.com.ORCID http://orcid.org/0000-0003-0341-4332

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The optimization of bovine embryo culture media is crucial for enhancing reproductive efficiency in livestock production. This comprehensive review evaluates the efficacy of specific growth factors and antioxidants used in bovine embryo culture, focusing on their impact on embryo development and viability. Bovine embryos are pivotal in agricultural practices, and the quality of embryo culture significantly influences pregnancy rates and overall herd productivity. This review synthesizes current research on the molecular mechanisms by which these supplements promote optimal embryo development, including pathways regulating cell proliferation, oxidative stress, and apoptosis. Practical implications for practitioners in bovine reproduction are outlined, with guidance on supplement concentrations, timing of administration, and formulation strategies to enhance embryo quality and increase pregnancy success. Furthermore, the review identifies gaps in current research and suggests future directions, such as exploring synergistic combinations of supplements, optimizing dose-response strategies, and assessing long-term effects post-transfer. In conclusion, optimizing culture media through the strategic use of growth factors and antioxidants is essential for advancing bovine reproductive technologies. This review serves as a valuable resource for researchers and practitioners aiming to improve the consistency and effectiveness of bovine in vitro embryo production, ultimately contributing to enhanced livestock productivity and sustainability.

Indexed as

AntioxidantsEmbryo Culture TechniquesEmbryonic DevelopmentFertilization in VitroIntercellular Signaling Peptides and ProteinsAnimalsCattleCulture MediaEmbryo TransferFemaleOxidative StressPregnancyAntioxidantsCulture MediaIntercellular Signaling Peptides and ProteinsBovine reproductionEmbryo developmentEmbryo productionReproduction

Identifiers

PMID40866739
PMCPMC12602790

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.