Evidence mapPaperPMID 40866940Full record

ArticleJournal of translational medicine2025

Association between bioelectrical impedance analysis parameters and muscle-related measurements obtained using a non-diagnostic ultrasound-based technique.

Giuseppe Annunziata, Ludovica Verde, Maria Grazia Tarsitano, Tiziana Stallone, Alessia Rosaria Anna Grillo, Maria Grazia Santaniello, Nadia Maria Venere Cristiano, Giovanni Ragozzino, Lucia Auletta, Massimiliano Caprio and 4 more

Abstract read
In one paragraph

Article in Journal of translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Giuseppe Annunziata *Facoltà di Scienze Umane, della Formazione e dello Sport, Università Telematica Pegaso, Via Porzio, Centro Direzionale, Isola F2, 80143, Naples, Italy. giuseppe.annunziata@unipegaso.it.ORCID 0000-0002-1922-662X
Ludovica Verde *Department of Public Health, University of Naples Federico II, Via Sergio Pansini 5, 80131, Naples, Italy.ORCID 0000-0002-4583-8283
Maria Grazia TarsitanoDepartment for the Promotion of Human Science and Quality of Life, San Raffaele Open University, Rome, Italy.ORCID 0000-0002-3500-0591
Tiziana StalloneDepartmental Faculty of Medicine, UniCamillus-Saint Camillus International University of Health Sciences, Via di Sant'Alessandro 8, 00131, Rome, Italy.
Alessia Rosaria Anna GrilloCORPO LIBERO S.S.D.R.L. Società Sportiva Dilettantistica, Via Ca' Silvestri 16, 35136, Padua, Italy.
Maria Grazia SantanielloDepartment of Experimental Medicine, Luigi Vanvitelli University of Campania, Naples, Italy.ORCID 0009-0002-1478-2894
Nadia Maria Venere CristianoDepartment of Experimental Medicine, Luigi Vanvitelli University of Campania, Naples, Italy.ORCID 0009-0009-3136-9840
Giovanni RagozzinoDepartment of Environmental, Biological and Pharmaceutical Sciences and Technologies (DISTABIF), Luigi Vanvitelli University of Campania, Caserta, Italy.ORCID 0000-0001-8239-0150
Lucia Auletta"Paolo Giaccone"University Hospital, Palermo, Italy.ORCID 0009-0004-1053-8776
Massimiliano CaprioDepartment for the Promotion of Human Science and Quality of Life, San Raffaele Open University, Rome, Italy.ORCID 0000-0003-0722-7163
Dale R WagnerKinesiology and Health Science, Utah State University, Logan, UT, USA.ORCID 0000-0003-1575-1555
Annamaria ColaoUnità di Endocrinologia, Diabetologia e Andrologia, Dipartimento di Medicina Clinica e Chirurgia, Università Degli Studi di Napoli Federico II, Via Sergio Pansini 5, 80131, Naples, Italy.ORCID 0000-0003-4049-2559
Giovanna Muscogiuri *Unità di Endocrinologia, Diabetologia e Andrologia, Dipartimento di Medicina Clinica e Chirurgia, Università Degli Studi di Napoli Federico II, Via Sergio Pansini 5, 80131, Naples, Italy.ORCID 0000-0002-8809-4931
Luigi Barrea *Dipartimento di Psicologia e Scienze della Salute, Università Telematica Pegaso, Via Porzio, Centro Direzionale Isola F2, 80143, Naples, Italy.ORCID 0000-0001-9054-456X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn in-depth analysis of body composition (BC) is fundamental for the assessment of nutritional status. A multifactorial approach is important for this assessment, integrating parameters and measurements obtained through different techniques, most notably bioelectrical impedance analysis (BIA) and ultrasound. In this study, we aimed to evaluate associations between BIA parameters and ultrasound measurements.

methodsThe BC of 993 adults (539 women and 454 men) was evaluated using BIA (BIA 101 RJL, Akern Bioresearch, Florence, Italy) and a non-diagnostic ultrasound-based technique at the thigh, employing a 2.5 MHz, A-mode probe (BodyMetrixTM, IntelaMetrix, Inc., Livermore, CA, USA). Ultrasound scans were analysed using Adipometria v 1.8.8 software (Hosand Technologies s.r.l., Verbania, Italy) and the muscle echogenicity (EG) was obtained. Ultrasound measurements were correlated with BIA parameters.

resultsIn the total population, muscle EG was directly correlated with the BIA parameter resistance (r = 0.347) and inversely correlated with several BIA parameters, including intracellular water (r = -0.479 and - 0.386, % and L, respectively) and phase angle (r = -0.487). These associations were maintained even after stratification of subjects by sex.

conclusionThe observation of significant associations between BIA parameters and ultrasound measurements suggests the importance of not considering the two methods as exclusive, but of integrating them into a holistic approach for the in-depth assessment of BC and nutritional status. Such an approach provides detailed information for the identification of optimal nutritional treatment, its monitoring over time, and possible optimisation.

Indexed as

Electric ImpedanceMusclesMuscle, SkeletalAdultAgedBody CompositionFemaleHumansMaleMiddle AgedUltrasonographyBioelectrical impedance analysisBody compositionMuscleNutritional statusUltrasound

Identifiers

PMID40866940
PMCPMC12392491

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.