Evidence map›Paper›PMID 40867323›Full record

ReviewCancers2025

Spatially Encoded Oncogenesis and Transcriptional Plasticity in Meningioma: Drivers of Therapeutic Resistance and Opportunities for Targeted Intervention.

Matthew A Abikenari, Amit Regev, Brandon H Bergsneider, Vratko Himic, Shreyas Annagiri, Lily H Kim, Ravi Medikonda, John Choi, Sanjeeva Jeyaretna, Daniel M Fountain and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Matthew A AbikenariDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0001-5835-5179
Amit RegevDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Brandon H BergsneiderDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0001-7013-8150
Vratko HimicDepartment of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0002-3906-5317
Shreyas AnnagiriDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Lily H KimDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Ravi MedikondaDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
John ChoiDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Sanjeeva JeyaretnaDepartment of Neurological Surgery, Oxford University Hospitals, University of Oxford, Oxford OX1 2JD, UK.
Daniel M FountainMRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX1 2JD, UK.
Michael LimDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whilst typically benign, a subset of meningiomas displays aggressive and recurrent behavior. There is a paucity of reliable treatment options for this subset of patients and a relative lack of consensus on how to best manage these patients. This clinical challenge reflects underlying molecular complexity, driven by

Indexed as

embryogenesismeningiomamolecular profilingtargeted therapiestranscriptomicstumor grading

Identifiers

PMID40867323
PMCPMC12384631

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.