Evidence map›Paper›PMID 40867567›Full record

ArticleBiomolecules2025

Dual Oxytocin Signals in Striatal Astrocytes.

Elisa Farsetti, Sarah Amato, Monica Averna, Diego Guidolin, Marco Pedrazzi, Guido Maura, Luigi Francesco Agnati, Chiara Cervetto, Manuela Marcoli

Abstract read
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Interaction Between Oxytocin and Dopamine Signaling: Focus on the Striatum.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elisa FarsettiDepartment of Pharmacy, University of Genova, Viale Cembrano 4, 16148 Genova, Italy.ORCID 0009-0004-5429-5745
Sarah AmatoDepartment of Pharmacy, University of Genova, Viale Cembrano 4, 16148 Genova, Italy.
Monica AvernaDepartment of Experimental Medicine, University of Genova, Viale Benedetto XV 1, 16132 Genova, Italy.ORCID 0000-0002-9463-7533
Diego GuidolinDepartment of Neuroscience, University of Padova, Via Gabelli 63, 35122 Padova, Italy.ORCID 0000-0003-2133-3552
Marco PedrazziDepartment of Experimental Medicine, University of Genova, Viale Benedetto XV 1, 16132 Genova, Italy.ORCID 0000-0001-7289-884X
Guido MauraDepartment of Earth, Environment and Life Sciences, University of Genova, Viale Benedetto XV 5, 16132 Genova, Italy.
Luigi Francesco AgnatiDepartment of Biomedical, Metabolic Sciences and Neuroscience, University of Modena and Reggio Emilia, 41121 Modena, Italy.
Chiara CervettoDepartment of Pharmacy, University of Genova, Viale Cembrano 4, 16148 Genova, Italy.ORCID 0000-0001-8290-3008
Manuela MarcoliDepartment of Earth, Environment and Life Sciences, University of Genova, Viale Benedetto XV 5, 16132 Genova, Italy.

Funding

FFABR (Fondo di finanziamento per le attività base di ricerca; MIUR-Italy) 2017 to CC and MM#NEXTGENERATIONEU (NGEU) and funded by the Italian Ministry of University and Research (MUR), National Recovery and Resilience Plan (NRRP), project MNESYS (PE0000006) - A Mul-tiscale integrated approach to the study of the nervous system in health and dis (DN. 1553 11.10.2022)Ph.D. School of the Department of Experimental Medicine (University of Genova) contribution 2021 to S.APh.D. School of the Department of Experimental Medicine (University of Genova) contribution 2023 to E.F
6 · The paper itself

Abstract

The ability of the neuropeptide oxytocin to affect glial cell function is receiving increasing attention. We previously reported that oxytocin at a low nanomolar concentration could inhibit both astrocytic Ca

Indexed as

AstrocytesCorpus StriatumOxytocinAnimalsCalciumCalcium SignalingGlutamic AcidMaleNeuronsRatsRats, WistarReceptors, OxytocinSignal TransductionCalciumGlutamic AcidOxytocinReceptors, Oxytocinastrocyte processesatosibanbiased agonistscarbetocinglutamate releaseintracellular calciumoxytocinoxytocin receptor

Identifiers

PMID40867567
PMCPMC12383634

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.