Evidence map›Paper›PMID 40867711›Full record

ArticleAnimals : an open access journal from MDPI2025

Grape Pomace and Ferulic Acid Improve Antioxidant Enzyme Activity and Gut Histomorphometry in Heat-Stressed Finishing Pigs.

María A Ospina-Romero, Leslie S Medrano-Vázquez, Araceli Pinelli-Saavedra, Miguel Ángel Barrera-Silva, Martín Valenzuela-Melendres, Miguel Ángel Martínez-Téllez, Reyna Fabiola Osuna-Chávez, María Del Refugio Robles-Burgueño, Humberto González-Rios

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

María A Ospina-RomeroCentro de Investigación en Alimentación y Desarrollo, A.C. Carretera Gustavo Enrique Astiazarán Rosas, No. 46, Col. La Victoria, Hermosillo 83304, Sonora, Mexico.
Leslie S Medrano-VázquezCentro de Investigación en Alimentación y Desarrollo, A.C. Carretera Gustavo Enrique Astiazarán Rosas, No. 46, Col. La Victoria, Hermosillo 83304, Sonora, Mexico.
Araceli Pinelli-SaavedraCentro de Investigación en Alimentación y Desarrollo, A.C. Carretera Gustavo Enrique Astiazarán Rosas, No. 46, Col. La Victoria, Hermosillo 83304, Sonora, Mexico.ORCID 0000-0003-1487-5767
Miguel Ángel Barrera-SilvaDepartamento de Agricultura y Ganadería, Universidad de Sonora, Carretera a Bahía de Kino km 21, Hermosillo 83000, Sonora, Mexico.
Martín Valenzuela-MelendresCentro de Investigación en Alimentación y Desarrollo, A.C. Carretera Gustavo Enrique Astiazarán Rosas, No. 46, Col. La Victoria, Hermosillo 83304, Sonora, Mexico.ORCID 0000-0002-7347-9599
Miguel Ángel Martínez-TéllezCentro de Investigación en Alimentación y Desarrollo, A.C. Carretera Gustavo Enrique Astiazarán Rosas, No. 46, Col. La Victoria, Hermosillo 83304, Sonora, Mexico.ORCID 0000-0003-2667-5455
Reyna Fabiola Osuna-ChávezDepartamento de Agricultura y Ganadería, Universidad de Sonora, Carretera a Bahía de Kino km 21, Hermosillo 83000, Sonora, Mexico.ORCID 0000-0001-6539-7828
María Del Refugio Robles-BurgueñoCentro de Investigación en Alimentación y Desarrollo, A.C. Carretera Gustavo Enrique Astiazarán Rosas, No. 46, Col. La Victoria, Hermosillo 83304, Sonora, Mexico.
Humberto González-RiosCentro de Investigación en Alimentación y Desarrollo, A.C. Carretera Gustavo Enrique Astiazarán Rosas, No. 46, Col. La Victoria, Hermosillo 83304, Sonora, Mexico.ORCID 0000-0002-7463-778X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the restrictions on animal growth promoters, alternative plant-based additives-particularly those rich in phenolic compounds, such as agro-industrial by-products-have been explored. These additives help to mitigate heat stress, which negatively affects productivity by impacting intestinal health and antioxidant status. This study evaluated the effects of individual and combined supplementation of ferulic acid (FA) and grape pomace (GP) on antioxidant enzyme activity, as well as intestinal histomorphometry, in finishing pigs under heat stress. Forty Yorkshire × Duroc pigs were randomly assigned to four treatments: control, 25 mg/kg FA, 2.5% GP, and MIX (FA + GP). FA supplementation increased intestinal villus height, while GP increased villus width in the duodenum and jejunum (

Indexed as

finishing pigsfunctional additiveheat stressintestinal healthphenolic compoundsphytogenic

Identifiers

PMID40867711
PMCPMC12382960

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.