Evidence mapPaperPMID 40868087Full record

ReviewBiomedicines2025

Gut-Brain Axis in Mood Disorders: A Narrative Review of Neurobiological Insights and Probiotic Interventions.

Gilberto Uriel Rosas-Sánchez, León Jesús Germán-Ponciano, Abraham Puga-Olguín, Mario Eduardo Flores Soto, Angélica Yanet Nápoles Medina, José Luis Muñoz-Carillo, Juan Francisco Rodríguez-Landa, César Soria-Fregozo

Abstract readReview
In one paragraph

Review in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gilberto Uriel Rosas-SánchezPrograma de Estancias Posdoctorales por México, Secretaría de Ciencia, Humanidades, Tecnología e Innovación SECIHTI, Centro Universitario de Los Lagos, Universidad de Guadalajara, Lagos de Moreno 47460, Jalisco, Mexico.ORCID 0000-0002-0753-0069
León Jesús Germán-PoncianoLaboratorio de Neurofarmacología, Instituto de Neuroetología, Universidad Veracruzana, Xalapa 91190, Veracruz, Mexico.ORCID 0000-0001-9185-2900
Abraham Puga-OlguínPrograma Investigadoras e Investigadores por México, SECIHTI-Centro de EcoAlfabetización y Diálogo de Saberes, Universidad Veracruzana, Xalapa 91060, Veracruz, Mexico.ORCID 0000-0002-5968-0210
Mario Eduardo Flores SotoLaboratorio de Neurobiología Celular y Molecular, División de Neurociencias, Centro de Investigación Biomédica de Occidente (CIBO), Instituto Mexicano del Seguro Social, Sierra Mojada 800, Independencia Oriente, Guadalajara 44340, Jalisco, Mexico.ORCID 0000-0002-5194-8569
Angélica Yanet Nápoles MedinaLaboratorio de Neurobiología Celular y Molecular, División de Neurociencias, Centro de Investigación Biomédica de Occidente (CIBO), Instituto Mexicano del Seguro Social, Sierra Mojada 800, Independencia Oriente, Guadalajara 44340, Jalisco, Mexico.ORCID 0009-0005-2583-6255
José Luis Muñoz-CarilloLaboratorio de Inmunología, Centro Universitario de los Lagos, Universidad de Guadalajara, Lagos de Moreno 47460, Jalisco, Mexico.ORCID 0000-0002-9403-1566
Juan Francisco Rodríguez-LandaLaboratorio de Neurofarmacología, Instituto de Neuroetología, Universidad Veracruzana, Xalapa 91190, Veracruz, Mexico.ORCID 0000-0001-5837-103X
César Soria-FregozoCentro Universitario de Los Lagos, Universidad de Guadalajara, Lagos de Moreno 47460, Jalisco, Mexico.ORCID 0000-0002-7829-6222

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota and its interaction with the nervous system through the gut-brain axis (MGB) have been the subject of growing interest in biomedical research. It has been proposed that modulation of microbiota using probiotics could offer a promising therapeutic alternative for mood regulation and the treatment of anxiety and depression disorders. The findings indicate that several probiotic strains, such as

Indexed as

antidepressantanxietyanxiolyticBifidobacteriumdepressionLactobacillusMGB Axisprobiotics

Identifiers

PMID40868087
PMCPMC12383312

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.