Evidence map›Paper›PMID 40868153›Full record

ReviewBiomedicines2025

Research Strategies and Methods of Hydrogels for Antitumor Drug Delivery.

Tianjiao Zeng, Lusi Chen, Toru Yoshitomi, Naoki Kawazoe, Yingnan Yang, Guoping Chen

Abstract readReview
In one paragraph

Review in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tianjiao ZengResearch Center for Macromolecules and Biomaterials, National Institute for Materials Science, Namiki 1-1, Tsukuba 305-0044, Ibaraki, Japan.ORCID 0000-0002-1286-0337
Lusi ChenResearch Center for Macromolecules and Biomaterials, National Institute for Materials Science, Namiki 1-1, Tsukuba 305-0044, Ibaraki, Japan.
Toru YoshitomiResearch Center for Macromolecules and Biomaterials, National Institute for Materials Science, Namiki 1-1, Tsukuba 305-0044, Ibaraki, Japan.ORCID 0000-0003-3847-1812
Naoki KawazoeResearch Center for Macromolecules and Biomaterials, National Institute for Materials Science, Namiki 1-1, Tsukuba 305-0044, Ibaraki, Japan.ORCID 0000-0003-3916-0709
Yingnan YangGraduate School of Life and Environment Science, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8572, Ibaraki, Japan.
Guoping ChenResearch Center for Macromolecules and Biomaterials, National Institute for Materials Science, Namiki 1-1, Tsukuba 305-0044, Ibaraki, Japan.ORCID 0000-0001-6753-3678

Funding

JSPS KAKENHI 19H04475JSPS KAKENHI 24K03289
6 · The paper itself

Abstract

Tumor treatments have substantially advanced through various approaches, including chemotherapy, radiotherapy, immunotherapy, and gene therapy. However, efficient treatment necessitates overcoming physiological barriers that impede the delivery of therapeutic agents to target sites. Drug delivery systems (DDSs) are a prominent research area, particularly in tumor therapy. This review provides a comprehensive overview of hydrogel-based DDSs for tumor treatment, focusing on the strategies and designs of DDSs based on the unique pathophysiological characteristics of tumors. The design and preparation of hydrogel systems for DDSs are summarized and highlighted. The challenges and opportunities for translating hydrogel-based DDSs into clinical applications are discussed.

Indexed as

antitumor therapycombination therapydrug delivery systemhydrogel

Identifiers

PMID40868153
PMCPMC12383573

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.