Evidence map›Paper›PMID 40868230›Full record

ArticleBiomedicines2025

Genetic Variants, Metabolic Dysfunction-Associated Fatty Liver Disease, and Major Health Outcomes in Older Adults.

Daniel Clayton-Chubb, Ammar Majeed, William W Kemp, Chenglong Yu, Peter W Lange, Jessica A Fitzpatrick, Robyn L Woods, Andrew M Tonkin, Andrew T Chan, Mark R Nelson and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Daniel Clayton-ChubbDepartment of Gastroenterology, Alfred Health, Melbourne 3004, Australia.ORCID 0000-0001-7479-9669
Ammar MajeedDepartment of Gastroenterology, Alfred Health, Melbourne 3004, Australia.
William W KempDepartment of Gastroenterology, Alfred Health, Melbourne 3004, Australia.ORCID 0000-0002-0787-7273
Chenglong YuSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.ORCID 0000-0002-0546-2779
Peter W LangeDepartment of Geriatrics and General Medicine, Werribee Mercy Hospital, Werribee 3030, Australia.
Jessica A FitzpatrickDepartment of Gastroenterology, Alfred Health, Melbourne 3004, Australia.ORCID 0000-0002-7811-8135
Robyn L WoodsSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.ORCID 0000-0003-1249-6149
Andrew M TonkinSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.
Andrew T ChanClinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA 02114, USA.
Mark R NelsonSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.ORCID 0000-0001-9941-7161
Joanne RyanSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.ORCID 0000-0002-7039-6325
Alexander D HodgeDepartment of Gastroenterology, Eastern Health, Melbourne 3128, Australia.ORCID 0000-0001-6680-2303
John S LubelDepartment of Gastroenterology, Alfred Health, Melbourne 3004, Australia.
Hans G SchneiderSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.
John J McNeilSchool of Public Health and Preventive Medicine, Monash University, Melbourne 3004, Australia.ORCID 0000-0002-1049-5129
Stuart K RobertsDepartment of Gastroenterology, Alfred Health, Melbourne 3004, Australia.ORCID 0000-0002-9015-7997

Funding

ASPirin in Reducing Events in the ElderlyU01AG029824 · NIA · HENNEPIN HEALTHCARE RESEARCH INSTITUTE · PI MCNEIL, JOHN JAMES, MURRAY, ANNE M · 2009 to 2018
$64.6M
Main Administrative CoreU19AG062682 · NIA · HENNEPIN HEALTHCARE RESEARCH INSTITUTE · PI CHAN, ANDREW T, MCNEIL, JOHN JAMES · 2019 to 2023
$42.9M
NCI NIH HHS U19AG062682NHMRC 334047, 1127060NIA NIH HHS U01 AG029824NIA NIH HHS U01AG029824NIA NIH HHS U19 AG062682NIH HHS 5U01AG029824-02NIH HHS U01AG029824; U19AG062682
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ageingcardiovascular diseaseepidemiologyfatty liver diseasegeneticsMAFLDMASLDmortalityolder adultssingle-nucleotide polymorphisms

Identifiers

PMID40868230
PMCPMC12383796

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.