Evidence map›Paper›PMID 40868286›Full record

ReviewBiomedicines2025

Glycomics in Human Diseases and Its Emerging Role in Biomarker Discovery.

Sherifdeen Onigbinde, Moyinoluwa Adeniyi, Oluwatosin Daramola, Favour Chukwubueze, Md Mostofa Al Amin Bhuiyan, Judith Nwaiwu, Tuli Bhattacharjee, Yehia Mechref

Abstract readReview
In one paragraph

Review in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Glycobiology in Human Health and Disease.International journal of molecular sciences · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sherifdeen OnigbindeDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0001-6791-7989
Moyinoluwa AdeniyiDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0009-0008-5088-4277
Oluwatosin DaramolaDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0002-0394-3683
Favour ChukwubuezeDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0002-2779-8564
Md Mostofa Al Amin BhuiyanDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.
Judith NwaiwuDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0002-7885-1345
Tuli BhattacharjeeDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.
Yehia MechrefDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0002-6661-6073

Funding

Sensitive and Quantitative MS-bases Glycomic Mapping PlatformR01GM112490 · NIGMS · TEXAS TECH UNIVERSITY · PI MECHREF, YEHIA · 2014 to 2024
$3.2M
Quantitative Characterization of Glycopeptide IsomersR01GM130091 · NIGMS · TEXAS TECH UNIVERSITY · PI Yehia Mechref · 2019 to 2026
$2.5M
NIGMS NIH HHS R01 GM112490NIGMS NIH HHS R01 GM130091NIH HHS 1R01GM112490-10NIH HHS 1R01GM130091-06The CH Foundation No NumberWelch Foundation D-0005
6 · The paper itself

Abstract

Glycosylation, the enzymatic addition of glycans to proteins and lipids, is a critical post-translational modification that influences protein folding, stability, trafficking, immune modulation, and cell signaling. The vast structural diversity of glycans arising from differences in monosaccharide composition, branching, and terminal modifications such as sialylation, fucosylation, and sulfation underpins their functional specificity and regulatory capacity. This review provides a comprehensive overview of glycan biosynthesis, with a focus on

Indexed as

cancer biomarkersglycan biosynthesisglycoengineeringglycomicsglycosylationimmune modulationneurodegenerative diseasetranslational glycobiology

Identifiers

PMID40868286
PMCPMC12383619

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.