Evidence map›Paper›PMID 40868475›Full record

ReviewChildren (Basel, Switzerland)2025

Growth Prediction in Orthodontics: ASystematic Review of Past Methods up to Artificial Intelligence.

Ioannis Lyros, Heleni Vastardis, Ioannis A Tsolakis, Georgia Kotantoula, Theodoros Lykogeorgos, Apostolos I Tsolakis

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ioannis LyrosDepartment of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-5897-6116
Heleni VastardisDepartment of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Ioannis A TsolakisDepartment of Orthodontics, School of Dentistry, Aristotle University of Thessaloniki, 54623 Thessaloniki, Greece.ORCID 0000-0002-5435-4889
Georgia KotantoulaDepartment of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-3322-9974
Theodoros Lykogeorgos"Hatzikosta" General Hospital of Messolonghi, 30200 Messolonghi, Greece.
Apostolos I TsolakisDepartment of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0003-3019-5438

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesGrowth prediction may be used by the clinical orthodontist in growing individuals for diagnostic purposes and for treatment planning. This process appraises chronological age and determines the degree of skeletal maturity to calculate residual growth. In developmental deviations, overlooking such diagnostic details might culminate in erroneous conclusions, unstable outcomes, recurrence, and treatment failure. The present review aims to systematically present and explain the available means for predicting growth in humans. Traditional, long-known, popular methods are discussed, and modern digital applications are described. MATERIALS AND

methodsA search on PubMed and the gray literature up to May 2025 produced 69 eligible studies on future maxillofacial growth prediction without any orthodontic intervention.

resultsSubstantial variability exists in the studies on growth prediction. In young orthodontic patients, the study of the lateral cephalometric radiography and the subsequent calculation of planes and angles remain questionable for diagnosis and treatment planning. Skeletal age assessment is readily accomplished with X-rays of the cervical vertebrae and the hand-wrist region. Computer software is being implemented to improve the reliability of classic methodologies. Metal implants have been used in seminal growth studies. Biochemical methods and electromyography have been suggested for clinical prediction and for research purposes.

conclusionsIn young patients, it would be of importance to reach conclusions on future growth with minimal distress to the individual and, also, reduced exposure to ionizing radiation. Nevertheless, the potential for comprehensive prediction is still largely lacking. It could be accomplished in the future by combining established methods with digital technology.

Indexed as

artificial intelligencecephalometric radiographycervical vertebraedeep learninggrowth predictionhand–wrist radiographymachine learningmetal implantsorthodontic treatment

Identifiers

PMID40868475
PMCPMC12384630

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.