Evidence map›Paper›PMID 40868508›Full record

ArticleChildren (Basel, Switzerland)2025

Examination of Behavioral and Neuropsychological Characteristics of Hungarian Patients with Juvenile Idiopathic Arthritis: A Cross-Sectional Analysis.

Diána Garan, Lilla Lengvári, Andrea Ponyi, Márton Szabados, Gyurgyinka Gergev, Imre Bozi, Wouter Wijker, Tamás Constantin

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In one paragraph

Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Diána GaranDivision of Pediatric Rheumatology and Immunology-Pediatric Center, Semmelweis University, Tűzoltó Street 7-9, 1094 Budapest, Hungary.
Lilla LengváriDivision of Pediatric Rheumatology and Immunology-Pediatric Center, Semmelweis University, Tűzoltó Street 7-9, 1094 Budapest, Hungary.
Andrea PonyiDivision of Pediatric Rheumatology and Immunology-Pediatric Center, Semmelweis University, Tűzoltó Street 7-9, 1094 Budapest, Hungary.
Márton SzabadosDivision of Pediatric Rheumatology and Immunology-Pediatric Center, Semmelweis University, Tűzoltó Street 7-9, 1094 Budapest, Hungary.
Gyurgyinka GergevDivision of Pediatric Rheumatology and Immunology-Pediatric Center, Semmelweis University, Tűzoltó Street 7-9, 1094 Budapest, Hungary.
Imre BoziAuxiliis Pharma Budapest Kft., 1037 Budapest, Hungary.
Wouter WijkerAuxiliis Pharma Budapest Kft., 1037 Budapest, Hungary.
Tamás ConstantinDivision of Pediatric Rheumatology and Immunology-Pediatric Center, Semmelweis University, Tűzoltó Street 7-9, 1094 Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildren with juvenile idiopathic arthritis (JIA) may experience chronic pain, contributing to psychological distress.

objectiveThe objective was to assess neuropsychological functions and behavioral skills in patients with JIA and identify demographic and disease-related factors influencing these outcomes.

methodsThis cross-sectional study evaluated 112 patients at the Division of Pediatric Rheumatology, Semmelweis University (2015-2016). Participants completed psychological assessments using the Child Behavior Checklist and Woodcock-Johnson III Tests. Examined variables included demographic (age and sex), clinical (age at diagnosis and disease activity), and treatment-related factors (therapy type and duration). Treatment groups comprised (a) combination therapy with TNF inhibitor and methotrexate (MTX) (n = 60), (b) MTX monotherapy (n = 34), and (c) TNF inhibitor monotherapy (n = 18).

resultsNeuropsychological variables showed no clinically significant differences between treatment groups. These skills were unaffected by age, sex, therapy duration, or disease activity. Pathological behavioral scores were significantly higher (

conclusionsNo clinically significant psychological impairments were observed in our cohort. Further research is warranted to clarify the significance of abnormal behavioral scores. Psychological care provision remains vital for improving the quality of life in JIA patients.

Indexed as

behaviorjuvenile arthritismood disorderspediatric rheumatologypsychology

Identifiers

PMID40868508
PMCPMC12384500

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