Evidence map›Paper›PMID 40868793›Full record

ArticleGels (Basel, Switzerland)2025

Photoactive Hydrogels as Materials for Biological Applications: Preparation of Thermally Stable Photoactive Films.

Oscar G Marambio, Lidia Álvarez, Héctor Díaz-Chamorro, Julio Sánchez, Rudy Martin-Trasancos, Christian Erick Palavecino, Guadalupe Del C Pizarro

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. CarbopolGels (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Oscar G MarambioDepartamento de Química, Facultad de Ciencias Naturales, Matemáticas y Medio Ambiente, Universidad Tecnológica Metropolitana (UTEM), J. P. Alessandri 1242, Santiago 7800002, Chile.
Lidia ÁlvarezDepartamento de Química, Facultad de Ciencias Naturales, Matemáticas y Medio Ambiente, Universidad Tecnológica Metropolitana (UTEM), J. P. Alessandri 1242, Santiago 7800002, Chile.
Héctor Díaz-ChamorroDepartamento de Química, Facultad de Ciencias Naturales, Matemáticas y Medio Ambiente, Universidad Tecnológica Metropolitana (UTEM), J. P. Alessandri 1242, Santiago 7800002, Chile.
Julio SánchezDepartamento de Química Orgánica, Facultad de Química y de Farmacia, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.ORCID 0000-0003-4245-0096
Rudy Martin-TrasancosDepartamento de Ingeniería Mecánica, Facultad de Ingeniería, Universidad de Santiago de Chile (USACH), Av. Bernardo O'Higgins 3363, Santiago 9170002, Chile.
Christian Erick PalavecinoLaboratorio de Microbiología Celular, Centro de Ciencias Médicas Aplicadas, Facultad de Medicina y Ciencias de la Salud, Universidad Central de Chile, Lord Cochrane 418, Santiago 8330546, Chile.ORCID 0000-0002-4581-7327
Guadalupe Del C PizarroDepartamento de Química, Facultad de Ciencias Naturales, Matemáticas y Medio Ambiente, Universidad Tecnológica Metropolitana (UTEM), J. P. Alessandri 1242, Santiago 7800002, Chile.ORCID 0000-0003-2063-1072

Funding

FONDECYT grant 1240357, 1231498, and 1241555.Research Continuity Project Fund, year 2023, Universidad Tecnológica Metropolitana. PY LCLI23-02,
6 · The paper itself

Abstract

Hydrogel materials have become an efficient, bioactive, and multifunctional alternative with great potential for biomedical applications. In this work, photoactive films were successfully designed for optical processing, and their photoactivity was tested in photodynamic therapy (PDT), such as antimicrobial patches. The stimulus-response hydrogel films are made of a hydrophilic polymer based on vinyl monomers, specifically 2-hydroxyethyl methacrylate (HEMA) and acrylamide (AAm), in a 1:1 molar ratio, along with the photochromic agent, 3,3-dimethylindolin-6'-nitrobenzoespiropirano (BSP), and a crosslinking agent, N,N'-methylenebisacrylamide (MBA). These hydrogel films were successfully created using the photoinitiator 2-hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone (IRGACURE 2959), MBA, and BSP in different concentrations (0.1, 0.3, and 0.5 mol%), which were later tested in photodynamic therapy (PDT) with the photosensitizer Ru(bpy)

Indexed as

bioinspired materialbiological applicationsstimulus-response hydrogel films

Identifiers

PMID40868793
PMCPMC12385473

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.