ArticleLife (Basel, Switzerland)2025
Assessment of the Association Between Coronary Artery Calcification, Plaque Vulnerability, and Perivascular Inflammation via Coronary CT Angiography.
Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic accuracy of coronary CT angiography versus invasive coronary angiography for detecting coronary artery disease: a systematic review and Bayesian meta-analysis.BMC medical imaging · 2026Pooled it
- Coronary inflammatory imaging and clinical factors: associations with coronary artery aneurysm regression in pediatric Kawasaki disease.The international journal of cardiovascular imaging · 2026Article
- Systemic inflammation affects the association between pericoronary fat attenuation index and adverse cardiovascular risk in patients with coronary artery disease.The international journal of cardiovascular imaging · 2026Article
- Coronary artery calcium score of zero in individuals with diabetes: association with normal coronary arteries and cardiovascular risk factors.The international journal of cardiovascular imaging · 2026Article
- CAPIRE score predicts long-term major cardiac events.The international journal of cardiovascular imaging · 2026Article
- Vessel-specific perivascular fat attenuation index derived from AI-CCTA and its association with impaired coronary flow reserve in patients with INOCA.International journal of cardiology. Heart & vasculature · 2026Article
- Coronary Plaque Vulnerability and Pericoronary Adipose Tissue Inflammation: Emerging Insights from Advanced CT Imaging.Medicina (Kaunas, Lithuania) · 2026Review
- Novel Hertz Contact Intravascular Lithotripsy: Could We Achieve More in Balloon-Based Calcium Modification?Journal of clinical medicine · 2026Review
- Diagnostic Accuracy Improvement of an Updated HEART Score to Predict Coronary Artery Disease as Detected by Coronary Computed Tomography Angiography.Journal of clinical medicine · 2026Article
- Retrospective Analysis of Incidental Myocardial Perfusion Defects on Non-ECG-Gated Contrast-Enhanced CT in Emergency Settings.Medicina (Kaunas, Lithuania) · 2026Article
- Percutaneous Coronary Intervention for Chronic Total Occlusions Modulates Cardiac Hypoxic and Inflammatory Stress.Journal of clinical medicine · 2026Article
- Cardiac CT in Non-Obstructive Coronary Artery Disease (NOCAD): A Literature Review.Journal of clinical medicine · 2025Review
- Evaluation of coronary artery calcium score by age and sex: a multicenter study.The international journal of cardiovascular imaging · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundCoronary artery calcium (CAC) scores are a widely used surrogate marker for atherosclerotic burden, but they do not fully reflect plaque vulnerability or coronary inflammation. This study aimed to evaluate the relationship between CACs, coronary plaque characteristics, and perivascular inflammatory activity using advanced CCTA and CaRi-Heart
methodsA total of 250 patients with no prior cardiovascular disease were retrospectively evaluated and stratified by CACs into three groups: 0 (
resultsSignificant differences across CAC categories were observed for several key parameters. The number of diseased coronary segments increased markedly (from 1.39 ± 1.10 vs. 2.97 ± 1.57 vs. 3.94 ± 2.10;
conclusionsThis study highlights the limitations of CACs as a standalone risk stratification tool. Vulnerable and inflamed plaques may already be present in patients with low or zero CACs. Integrating CCTA with perivascular FAI mapping enables earlier detection of biologically active atherosclerosis and supports more precise clinical decision-making.
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