ArticleInternational journal of molecular sciences2025
Characteristics and Potential of KSL, KSL-W, and Dadapin-1 Antimicrobial Peptides for Preventing Infections of Orthopedic Prosthetic Devices: Identifying the Most Robust Candidate.
Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
10 authors.
Davide CampocciaLaboratorio di Patologia delle Infezioni Associate all'Impianto, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy.ORCID 0000-0002-3336-0219
Andrea De DonnoLaboratorio di Patologia delle Infezioni Associate all'Impianto, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy.ORCID 0009-0008-4401-2149
Giulia BottauLaboratorio di Patologia delle Infezioni Associate all'Impianto, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy.
Gloria BuaLaboratorio di Patologia delle Infezioni Associate all'Impianto, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy.ORCID 0000-0003-0826-3713
Stefano RavaioliLaboratorio di Patologia delle Infezioni Associate all'Impianto, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy.ORCID 0000-0001-5364-6196
Eleonora CapponiLaboratorio di Patologia delle Infezioni Associate all'Impianto, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy.
Giovanna SotgiuInstitute for Organic Synthesis and Photoreactivity (ISOF), National Research Council, Via Gobetti 101, 40129 Bologna, Italy.ORCID 0000-0003-3590-714X
Francesco PegreffiDepartment of Medicine and Surgery, School of Medicine and Surgery, "Kore" University of Enna, 94100 Enna, Italy.ORCID 0000-0002-6788-6040
Silvia CostantiniDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Via San Giacomo 14, 40126 Bologna, Italy.
Carla Renata ArciolaDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Via San Giacomo 14, 40126 Bologna, Italy.ORCID 0000-0003-0382-0066
Funding
University of Bologna - DIMEC BUS25Q7_patobioclinica-bus25/ Pallotti 16962
6 · The paper itself
Abstract
Antimicrobial peptides (AMPs) are increasingly emerging as alternatives to conventional antibiotics. This study compared the antibacterial activity of two decapeptides, KSL and KSL-W, and a 23-residue peptide, Dadapin-1, against bacterial species that colonize orthopedic implants, with the aim of identifying the most effective peptide for future AMP-based anti-infective orthopedic biomaterials.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.