Evidence mapPaperPMID 40869189Full record

ArticleInternational journal of molecular sciences2025

Youngji Han, Seung Pil Pack

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Youngji HanBio-Medical Research Institute, Kyungpook National University Hospital, Daegu 41940, Republic of Korea.ORCID 0000-0003-2270-8176
Seung Pil PackBiological Clock-Based Anti-Aging Convergence RLRC, Korea University, Sejong-ro 2511, Sejong 30019, Republic of Korea.

Funding

National Research Foundation of Korea RS-2021-NR059450National Research Foundation of Korea RS-2021-NR060107
6 · The paper itself

Abstract

Sarcopenia, the age-related decline in skeletal muscle mass and function, is a growing health concern in aging populations. Nutritional interventions are increasingly recognized for their therapeutic potential; however, molecular biomarkers that reflect their efficacy are limited. To identify nutrition-responsive genes relevant to sarcopenia, we performed transcriptomic profiling of gastrocnemius muscle from mature and middle-aged mice. Aging-associated differentially expressed genes (DEGs) were filtered based on expression levels and correlation with muscle mass. Functional food interventions, including high- and low-molecular-weight collagen hydrolysates and allulose, were applied, and effect scores were calculated to assess transcriptomic responsiveness.

Indexed as

AgingSarcopeniaAnimalsBiomarkersDietary SupplementsGene Expression ProfilingMaleMiceMice, Inbred C57BLMuscle, SkeletalTranscriptomeBiomarkersAjubanutritional therapynutrition-responsive biomarkersarcopenia

Identifiers

PMID40869189
PMCPMC12386266

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.