Evidence map›Paper›PMID 40869206›Full record

ReviewInternational journal of molecular sciences2025

Biomarkers and Clinical Evaluation in the Detection of Frailty.

Catherine Devitt, Devon Patel, Rustin Mahboubi Ardakani, Shaji Poovathoor, Zhaosheng Jin, Daryn Moller

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. A multidimensional approach to frailty in emergency surgery for perforated peptic ulcer.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Catherine DevittDepartment of Anesthesiology, Stony Brook University Hospital, Health Sciences Center, Level 4, Room 060, Stony Brook, NY 11794, USA.
Devon PatelDepartment of Anesthesiology, Stony Brook University Hospital, Health Sciences Center, Level 4, Room 060, Stony Brook, NY 11794, USA.
Rustin Mahboubi ArdakaniRenaissance School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA.
Shaji PoovathoorDepartment of Anesthesiology, Stony Brook University Hospital, Health Sciences Center, Level 4, Room 060, Stony Brook, NY 11794, USA.
Zhaosheng JinDepartment of Anesthesiology, Stony Brook University Hospital, Health Sciences Center, Level 4, Room 060, Stony Brook, NY 11794, USA.ORCID 0000-0002-2495-7048
Daryn MollerDepartment of Anesthesiology, Stony Brook University Hospital, Health Sciences Center, Level 4, Room 060, Stony Brook, NY 11794, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Frailty is a complex biological process that is associated with adverse outcomes in community-dwelling and hospitalized patients. While clinical evaluation is the current gold standard for screening and diagnosis, such an approach is not without its limitations (such as personnel and resource requirement). In this review, we will discuss prospective biomarkers for frailty. Opportunistic and deliberate radiological testing could provide important information that complements clinical frailty evaluation. Novel biochemical panels may yield additional methods for frailty screening in the future. It is known that early frailty intervention could lead to better outcomes for patients. Integration of electronic medical records, laboratory and radiological results, as well as clinical informatics infrastructure could result in augmented clinical decision-making and more optimized healthcare resources utilization.

Indexed as

BiomarkersFrailtyAgedFrail ElderlyGeriatric AssessmentHumansBiomarkersbiomarkerdiagnosisfrailtyinflammationmetabolomicsoxidative stressscreening

Identifiers

PMID40869206
PMCPMC12386657

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.