Evidence map›Paper›PMID 40869273›Full record

ArticleInternational journal of molecular sciences2025

Adam J Farmer, Mark H Inlow, Shaad M Ahmad, Kristopher R Schwab

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adam J FarmerDepartment of Biology, Indiana State University, Terre Haute, IN 47809, USA.ORCID 0000-0002-6908-5650
Mark H InlowThe Center for Genomic Advocacy, Indiana State University, Terre Haute, IN 47809, USA.
Shaad M AhmadDepartment of Biology, Indiana State University, Terre Haute, IN 47809, USA.ORCID 0000-0001-5373-1710
Kristopher R SchwabDepartment of Biology, Indiana State University, Terre Haute, IN 47809, USA.ORCID 0000-0001-8056-1817

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
NIH HHS P40 OD018537
6 · The paper itself

Abstract

The Complex Proteins Associated with Set1 (COMPASS)-like complex regulates developmental gene expression via histone 3 lysine 4 (H3K4) methylation and other transcriptional mechanisms. Several members of the lysine methyltransferase 2C and D (KMT2C/D)-COMPASS-like complex are implicated in human congenital heart and vascular defects. The investigation of the orthologous Trithorax-related (Trr)-COMPASS-like complex in

Indexed as

Carrier ProteinsCell DivisionDrosophila melanogasterDrosophila ProteinsHeartNuclear ProteinsStem CellsAnimalsGene Expression Regulation, DevelopmentalHistone-Lysine N-MethyltransferaseHistonesMethylationRepressor ProteinsTrans-ActivatorsTranscription FactorsCarrier ProteinsDrosophila ProteinsHistone-Lysine N-MethyltransferaseHistonesNuclear ProteinsRepressor Proteinstin protein, DrosophilaTrans-ActivatorsTranscription FactorsTRR protein, Drosophilacardiac progenitor cell divisioncardiogenesisCOMPASS complexDrosophilaheart development and diseaseKabuki SyndromeKMT2C/DMLL3/4PtipSet1trrtrx

Identifiers

PMID40869273
PMCPMC12386242

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.