Evidence map›Paper›PMID 40869418›Full record

ArticleInternational journal of molecular sciences2025

Heterogeneous Macrophage Activation in Acute Skeletal Muscle Sterile Injury and

Xingyu Wang, Justin K Moy, Yinhang Wang, Gregory R Smith, Frederique Ruf-Zamojski, Pawel F Przytycki, Stuart C Sealfon, Lan Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xingyu WangDepartment of Neurology, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.ORCID 0000-0001-9097-9627
Justin K MoyGraduate Program in Bioinformatics, Boston University, 24 Cummington Mall, Boston, MA 02215, USA.ORCID 0000-0002-7566-2215
Yinhang WangDepartment of Neurology, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.ORCID 0009-0008-4427-0164
Gregory R SmithDepartment of Neurology, Icahn School of Medicine at Mount Sinai, 1468 Madison Avenue, New York, NY 10029, USA.
Frederique Ruf-ZamojskiDepartment of Neurology, Icahn School of Medicine at Mount Sinai, 1468 Madison Avenue, New York, NY 10029, USA.
Pawel F PrzytyckiGraduate Program in Bioinformatics, Boston University, 24 Cummington Mall, Boston, MA 02215, USA.ORCID 0000-0002-3360-6936
Stuart C SealfonDepartment of Neurology, Icahn School of Medicine at Mount Sinai, 1468 Madison Avenue, New York, NY 10029, USA.
Lan ZhouDepartment of Neurology, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.

Funding

Predoctoral Training in Bioinformatics and Computational BiologyT32GM100842 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI TULLIUS, THOMAS D · 2012 to 2022
$2.8M
Origins and Functions of Intramuscular Macrophages in Duchenne Muscular DystrophyR01AR074428 · NIAMS · HOSPITAL FOR SPECIAL SURGERY · PI ZHOU, LAN · 2019 to 2023
$1.8M
NIAMS NIH HHS R01 AR074428NIGMS NIH HHS T32 GM100842NIH HHS 1R01AR074428-01
6 · The paper itself

Abstract

Monocytes/macrophages promote the repair of acutely injured muscle while contributing to dystrophic changes in chronically injured muscle in Duchenne muscular dystrophy (DMD) patients and animal models including

Indexed as

Macrophage ActivationMacrophagesMuscle, SkeletalMuscular Dystrophy, DuchenneAnimalsDisease Models, AnimalGene Expression ProfilingMaleMiceMice, Inbred C57BLMice, Inbred mdxMonocytesTranscriptomeinflammationmacrophagesmuscle injurymuscular dystrophy

Identifiers

PMID40869418
PMCPMC12387070

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.