SynthesisGenes2025
Genome-Wide Association Study and Meta-Analysis Uncovers Key Candidate Genes for Body Weight Traits in Chickens.
Synthesis in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Weighted single-step GWAS identified candidate genes associated with semen traits in Rhode Island Red chickens.Poultry science · 2026Article
- Genomic Insights into Abdominal and Intramuscular Fat Deposition in Chickens and Their Implications for Productivity Traits: A Systematic Review.Animals : an open access journal from MDPI · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundGenome-wide association studies (GWAS) have been extensively employed to elucidate the genetic architecture of body weight (BW) traits in chickens, which represent key economic indicators in broiler production. With the growing availability of genomic data from diverse commercial and resource chicken populations, a critical challenge lies in how to effectively integrate these datasets to enhance sample size and thereby improve the statistical power for detecting genetic variants associated with complex traits.
methodsIn this study, we performed a multi-population GWAS meta-analysis on BW traits across three genetically distinct chicken populations, focusing on BW at 56, 70, and 84 days of age: P1 (N301 Yellow Plumage Dwarf Chicken Line;
resultsCompared to single-population GWAS, our meta-analysis identified 77 novel independent variants significantly associated with BW traits, while gene-based association analysis implicated 59 relevant candidate genes. Functional annotation of BW56- and BW84-associated SNPs (single-nucleotide polymorphisms) 1_170526144G>T and 1_170642110A>G, integrated with tissue-specific regulatory annotations, revealed significant enrichment of enhancer and promoter elements for
conclusionsThese findings provide valuable mechanistic insights into the genetic mechanisms underlying body weight regulation in poultry and offer important references for selective breeding strategies aimed at improving production efficiency in the poultry industry.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.