Evidence map›Paper›PMID 40870694›Full record

ArticleFoods (Basel, Switzerland)2025

Untargeted Metabolomics Uncovers Food Safety Risks: Polystyrene Nanoplastics Induce Metabolic Disorders in Chicken Liver.

Xuan Hu, Yinyin Liu, Yinpeng Ma, Jing Zhang, Lina Ma, Wanqiang Chen, Xiujun Tang, Junxian Lu, Lingzhi Chen, Guodong Cai and 2 more

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xuan HuJiangsu Institute of Poultry Science, Yangzhou 225009, China.ORCID 0009-0004-2576-9825
Yinyin LiuJiangsu Institute of Poultry Science, Yangzhou 225009, China.
Yinpeng MaJiangsu Institute of Poultry Science, Yangzhou 225009, China.
Jing ZhangJiangsu Institute of Poultry Science, Yangzhou 225009, China.ORCID 0000-0003-4772-7648
Lina MaJiangsu Institute of Poultry Science, Yangzhou 225009, China.
Wanqiang ChenJiangsu Institute of Poultry Science, Yangzhou 225009, China.
Xiujun TangJiangsu Institute of Poultry Science, Yangzhou 225009, China.
Junxian LuJiangsu Institute of Poultry Science, Yangzhou 225009, China.
Lingzhi ChenCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Guodong CaiCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Jianchun BianCollege of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.ORCID 0000-0001-8023-0751
Yushi GaoJiangsu Institute of Poultry Science, Yangzhou 225009, China.

Funding

Innovation Funds for Agricultural Science and Technology in Jiangsu Province CX(21)2011Priority Academic Program Development of Jiangsu Higher Education Institutions 111 Project (D18007)Sub-project of the Agricultural Industry Technology System of Jiangsu Province JATS [2023] 363
6 · The paper itself

Abstract

Polystyrene nanoplastics (NPs) threaten agricultural ecosystems and the food chain; however, their hepatotoxicity in chickens, a key poultry species, remains unclear. This study investigated the effects of chronic NP exposure on hepatic metabolism to evaluate food safety risks in poultry products. Chickens were orally exposed to 100 nm polystyrene NPs via feed for 120 days. Histopathological evaluation, serum biochemical analysis revealed hepatotoxicity in NP-exposed poultry, characterized by histopathological liver injury, elevated lipid droplet accumulation, significantly increased alanine aminotransferase (ALT) activity, and elevated triglyceride (TG) levels (

Indexed as

chickenfood safetyLC-MS/MS metabolomicslivermetabolic disruptionnanoplastics

Identifiers

PMID40870694
PMCPMC12385707

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.