Evidence map›Paper›PMID 40870842›Full record

ReviewDiagnostics (Basel, Switzerland)2025

Endoscopic Diagnostics for IgG4-Related Pancreatobiliary Diseases: Current Modalities and Clinical Perspectives.

Itaru Naitoh, Michihiro Yoshida, Takahiro Nakazawa

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Itaru NaitohDepartment of Gastroenterology, Nagoya City University Midori Municipal Hospital, Nagoya 458-0037, Japan.ORCID 0000-0001-8342-886X
Michihiro YoshidaDepartment of Gastroenterology, Nagoya City University Graduate School of Medical Sciences, Nagoya 458-0037, Japan.ORCID 0000-0002-4167-2781
Takahiro NakazawaDepartment of Gastroenterology, Nagoya City University Graduate School of Medical Sciences, Nagoya 458-0037, Japan.

Funding

Japan Society for the Promotion of Science JP25K11258
6 · The paper itself

Abstract

Type 1 autoimmune pancreatitis (AIP), IgG4-related sclerosing cholangitis (IgG4-SC), and IgG4-related cholecystitis are recognized as IgG4-related pancreatobiliary diseases. Endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasonography (EUS) are crucial diagnostic modalities for these conditions. In the diagnosis of AIP, EUS-guided tissue acquisition plays an important role in obtaining histological confirmation and excluding pancreatic cancer (PC). EUS, including contrast-enhanced harmonic imaging and elastography, is used to differentiate focal-type AIP from PC. Endoscopic retrograde pancreatography (ERP) is utilized to obtain a pancreatogram when it is challenging to distinguish AIP from pancreatic cancer. Duodenal papilla biopsy may serve as a supplementary tool, particularly in cases involving the pancreatic head. Cholangiographic classification is essential for differentiating IgG4-SC from PC, primary sclerosing cholangitis (PSC), and cholangiocarcinoma (CCA). ERCP is commonly performed for additional ERCP-related procedures. Intraductal ultrasonography (IDUS) is useful for distinguishing IgG4-SC from CCA or PSC. The primary role of bile duct biopsy is exclusion of malignant biliary strictures; EUS-guided tissue acquisition may also provide histological evidence of IgG4-SC. In the diagnosis of IgG4-related cholecystitis, EUS is helpful to differentiate it from gallbladder cancer. EUS-guided tissue acquisition can aid in confirming IgG4-related cholecystitis and excluding gallbladder cancer or xanthogranulomatous cholecystitis. Transpapillary gallbladder cytology or biopsy may also be considered. Overall, endoscopic modalities play a critical role in diagnosing IgG4-related pancreatobiliary diseases.

Indexed as

autoimmune pancreatitisendoscopic retrograde cholangiopancreatographyendoscopic ultrasonographyIgG4-related cholecystitisIgG4-related diseaseIgG4-related pancreatobiliary diseaseIgG4-related sclerosing cholangitisintraductal ultrasonography

Identifiers

PMID40870842
PMCPMC12385287

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.