Evidence mapPaperPMID 40871617Full record

ReviewNutrients2025

Assessment of Sarcopenia in Patients with Liver Cirrhosis-A Literature Review.

Dorotea Bozic, Bisera Mamic, Iva Peric, Ivona Bozic, Ivan Zaja, Tomislav Ivanovic, Ana Gugic Ratkovic, Ivica Grgurevic

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Bioimpedance Analysis to Predict Clinical Outcomes of Liver Cirrhosis in a Prospective Cohort Study.JGH open : an open access journal of gastroenterology and hepatology · 2026
    Article
  2. Endoscopic Papillectomy for Ampullary Tumors in Older Patients: Balancing Oncologic Benefit and Geriatric Risk.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dorotea BozicDepartment of Gastroenterology, University Hospital of Split, Spinciceva 1, 21000 Split, Croatia.
Bisera MamicDepartment of Oncology and Radiotherapy, University Hospital of Split, Spinciceva 1, 21000 Split, Croatia.
Iva PericDepartment of Radiology and Interventional Radiology, University Hospital of Split, Spinciceva 1, 21000 Split, Croatia.
Ivona BozicDepartment of Rheumatology and Immunology, University Hospital of Split, Soltanska 2, 21000 Split, Croatia.
Ivan ZajaDepartment of Gastroenterology, University Hospital of Split, Spinciceva 1, 21000 Split, Croatia.
Tomislav IvanovicDepartment of Abdominal Surgery, University Hospital of Split, Spinciceva 1, 21000 Split, Croatia.
Ana Gugic RatkovicFaculty of Food Technology and Biotechnology, University of Zagreb, Pierrotijeva 6, 10000 Zagreb, Croatia.
Ivica GrgurevicDepartment of Gastroenterology, Hepatology and Clinical Nutrition, Clinical Hospital Dubrava, Avenija Gojka Suska 6, 10000 Zagreb, Croatia.ORCID 0000-0003-0520-3483

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcopenia refers to a disorder involving the gradual and overall reduction in skeletal muscle mass and physical capability. It occurs in over one-third of individuals with liver cirrhosis and serves as an independent predictor of increased mortality risk. Assessment of sarcopenia is necessary in all patients with liver cirrhosis, as recommended by the European Association for the Study of the Liver (EASL) and the European Society for Clinical Nutrition and Metabolism (ESPEN). The evaluation of muscle mass can be performed using several validated methods such as the multislice computed tomography (MSCT), abdominal magnetic resonance imaging (MRI), dual X-ray absorptiometry (DXA), bioelectrical impedance analysis (BIA), or muscle ultrasound. Assessment of muscle function encompasses measurements of both muscle strength and physical performance. Sarcopenia has a significant negative impact on the course of the disease, quality of life and outcomes of patients with liver cirrhosis. Considering the global healthcare impact and the significant influence on the course of disease, characteristics of simplicity, swiftness, safety, availability, reproducibility, and diagnostic accuracy are certainly the key factors to consider when choosing the proper diagnostic method for nutritional assessment. The aim of this review is to analyze the pathophysiological mechanisms underlying muscle mass loss in patients with liver cirrhosis, as well as to assess strengths and limitations of the methods currently in use to diagnose sarcopenia.

Indexed as

Liver CirrhosisSarcopeniaAbsorptiometry, PhotonElectric ImpedanceHumansMagnetic Resonance ImagingMuscle, SkeletalMuscle StrengthNutrition AssessmentQuality of LifeReproducibility of ResultsUltrasonographyBIAL3-SMIliver cirrhosismuscle thicknesssarcopenia

Identifiers

PMID40871617
PMCPMC12388875

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.