Evidence map›Paper›PMID 40871644›Full record

Observational studyNutrients2025

Impact of Sarcopenic Diabetes on Outcomes and Mortality in Older Adults Hospitalized for Hip Fracture: A Nested Case-Control Study Within a Real-World Evidence Cohort.

Elisa García-Tercero, Daniela Villalon Rubio, Ángel Belenguer-Varea, Cristina Cunha-Pérez, José Viña, Francisco José Tarazona-Santabalbina

Abstract readObservational Study
In one paragraph

Observational study in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elisa García-TerceroGeriatric Medicine Department, Hospital Universitario de la Ribera, 46600 Alzira, Spain.
Daniela Villalon RubioGeriatric Medicine Department, Hospital Universitario de la Ribera, 46600 Alzira, Spain.ORCID 0009-0003-3185-0550
Ángel Belenguer-VareaGeriatric Medicine Department, Hospital Universitario de la Ribera, 46600 Alzira, Spain.ORCID 0000-0002-0518-6612
Cristina Cunha-PérezSchool of Doctorate, Universidad Católica de Valencia San Vicente Mártir, 46001 Valencia, Spain.
José ViñaCentro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES), 28029 Madrid, Spain.
Francisco José Tarazona-SantabalbinaGeriatric Medicine Department, Hospital Universitario de la Ribera, 46600 Alzira, Spain.ORCID 0000-0003-4531-1446

Funding

ABBOTT generic grant
6 · The paper itself

Abstract

backgroundThis study addresses the prevalence and outcomes of sarcopenic diabetes among older adults hospitalized for hip fractures, highlighting its association with nutritional status, frailty, in-hospital outcomes, and mortality. With the global incidence of hip fractures anticipated to rise significantly, understanding these associations is crucial, especially considering the higher prevalence of sarcopenia in diabetic patients, which exacerbates outcomes.

methodsAn observational, unicentric case-control study nested within a real-world data cohort was conducted. It included 2631 older adults (aged ≥ 70 years) hospitalized for hip fractures at the Hospital Universitario de la Ribera, Spain, from 2014 to 2021. Diabetic patients were classified as cases, and non-diabetic patients served as controls. The study examined demographic variables, comorbidities, nutritional status, geriatric syndromes, and mortality, using the SARC-F questionnaire for sarcopenia screening.

resultsThe study found that cases (diabetic patients) presented with higher comorbidities, longer hospital stays, and a higher prevalence of sarcopenia, significantly impacting in-hospital and long-term mortality rates. The prevalence of possible sarcopenia was notably higher at 61.5% among diabetic patients. Sarcopenia was strongly correlated with worse functional outcomes and higher mortality.

conclusionsSarcopenic diabetes significantly increases the risk of adverse outcomes and mortality in older adults with hip fractures. The findings underscore the importance of routine screening for diabetes and sarcopenia in this patient population to mitigate risks and improve rehabilitation outcomes.

Indexed as

Diabetes ComplicationsDiabetes MellitusHip FracturesSarcopeniaAgedAged, 80 and overCase-Control StudiesCohort StudiesComorbidityFemaleHospitalizationHospital MortalityHumansLength of StayMaleNutritional Statusfrailtyhip fracturesin-hospital outcomesmortalitynutritional statusolder adultssarcopenia screeningsarcopenic diabetes

Identifiers

PMID40871644
PMCPMC12389665

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.