Evidence map›Paper›PMID 40871663›Full record

ArticleNutrients2025

High Prevalence of Vitamin D Deficiency in Patients Undergoing Total Shoulder or Elbow Arthroplasty.

Miledi Hoxha, Tizian Heinz, Maximilian Rudert, Kilian List, Leonard Achenbach, Gerrit Maier, Manuel Weißenberger, Konstantin Horas

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Miledi HoxhaOrthopaedic Center for Musculoskeletal Research, University of Wuerzburg, 97074 Wuerzburg, Germany.
Tizian HeinzDepartment of Orthopaedic Surgery, Koenig-Ludwig-Haus, University of Wuerzburg, 97074 Wuerzburg, Germany.
Maximilian RudertOrthopaedic Center for Musculoskeletal Research, University of Wuerzburg, 97074 Wuerzburg, Germany.ORCID 0000-0003-4982-6594
Kilian ListDepartment of Orthopaedic Surgery, Koenig-Ludwig-Haus, University of Wuerzburg, 97074 Wuerzburg, Germany.ORCID 0000-0002-9965-1799
Leonard AchenbachDepartment of Orthopaedic Surgery, Koenig-Ludwig-Haus, University of Wuerzburg, 97074 Wuerzburg, Germany.
Gerrit MaierDepartment of Orthopaedic Surgery, Pius-Hospital, Carl-von-Ossietzky-University, 26129 Oldenburg, Germany.
Manuel WeißenbergerOrthopaedic Center for Musculoskeletal Research, University of Wuerzburg, 97074 Wuerzburg, Germany.
Konstantin HorasOrthopaedic Center for Musculoskeletal Research, University of Wuerzburg, 97074 Wuerzburg, Germany.ORCID 0000-0002-9086-3541

Funding

Deutsche Arthrosehilfe e.V. Deutsche Arthrosehilfe e.V. (Grant Number P55A284_Horas/Heinz/Rudert)
6 · The paper itself

Abstract

backgroundVitamin D deficiency represents a global health problem of enormous extent. It is estimated that around one billion people worldwide have inadequate vitamin D levels. This phenomenon is directly associated with negative impact on a variety of orthopaedic conditions. Further, there is now robust evidence that perioperative vitamin D levels in patients scheduled for total joint replacement (TJA) affect outcome and the healing process. To date, only few studies focus on vitamin D levels of patients scheduled for total arthroplasty of the upper extremity (shoulder and elbow). For this reason, the objective of this study is to determine the prevalence of vitamin D deficiency in this patient collective.

methodsIn a monocentric cohort study, serum levels of 25-hydroxyvitamin D (25OHD) were measured preoperatively in all patients undergoing total shoulder or elbow arthroplasty. Demographic and perioperative data as well as comorbidities were recorded from medical records to assess for potential risk factors for hypovitaminosis D. Multivariate regression analyses were used to identify risk factors for vitamin D insufficiency and deficiency.

resultsCollectively, 108 patients with total joint replacement of the upper extremity were included over a period of twelve months. Notably, 28.7% (31/108) of patients reported a regular intake of vitamin D supplements. 62.3% (19/31) of those had sufficient vitamin D levels, while 38.7% (12/31) had insufficient and further 6% (2/31) deficient vitamin D levels (<20 ng/mL). Remarkably, 87% of patients that did not report a regular vitamin D intake (

conclusionPatients undergoing total shoulder or elbow arthroplasty have an increased risk profile for hypovitaminosis D (vitamin D supplementation had 94% lower odds of being deficient; OR = 0.06,

Indexed as

Arthroplasty, Replacement, ElbowArthroplasty, Replacement, ShoulderVitamin D DeficiencyAgedAged, 80 and overCohort StudiesDietary SupplementsFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsVitamin D25-hydroxyvitamin DVitamin Djoint replacementtotal shoulder arthroplastyvitamin Dvitamin D deficiency

Identifiers

PMID40871663
PMCPMC12389540

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.