Evidence map›Paper›PMID 40871685›Full record

Trial reportNutrients2025

Chlorella-Induced Increase in Cardiac Function Further Enhances Aerobic Capacity Through High-Intensity Intermittent Training in Healthy Young Men and Rats.

Shumpei Fujie, Kenichiro Inoue, Katsunori Tsuji, Naoki Horii, Moe Oshiden, Izumi Tabata, Motoyuki Iemitsu

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shumpei FujieFaculty of Sport and Health Science, Ritsumeikan University, Kusatsu 525-8577, Japan.
Kenichiro InoueFaculty of Sport and Health Science, Ritsumeikan University, Kusatsu 525-8577, Japan.
Katsunori TsujiFaculty of Sport and Health Science, Ritsumeikan University, Kusatsu 525-8577, Japan.
Naoki HoriiJapan Society for the Promotion of Science, Tokyo 102-0083, Japan.
Moe OshidenFaculty of Sport and Health Science, Ritsumeikan University, Kusatsu 525-8577, Japan.
Izumi TabataFaculty of Sport and Health Science, Ritsumeikan University, Kusatsu 525-8577, Japan.ORCID 0000-0001-9938-6529
Motoyuki IemitsuFaculty of Sport and Health Science, Ritsumeikan University, Kusatsu 525-8577, Japan.ORCID 0000-0003-4362-6030

Funding

Japan Society for the Promotion of Science 23K24744Sun Chlorella Corp. None
6 · The paper itself

Abstract

backgroundChronic chlorella intake combined with high-intensity intermittent training (HIIT) has been shown to accelerate aerobic and anaerobic capacities in rodents. This study aimed to clarify the effects of combining chlorella intake with short-term HIIT on exercise performance in humans, and to investigate the impact of chlorella intake on cardiac adaptation. MATERIALS AND

methodsIn Study 1, twelve healthy young men completed a 3-week exhaustive HIIT, comprising 6-7 bouts of 20 s of cycling on a leg ergometer at an intensity of 170% maximal oxygen uptake (V˙O

results[Study 1] After each HIIT, V˙O

conclusionsChronic chlorella intake, which improves aerobic capacity by enhancing cardiac function without causing cardiac maladaptation, combined with short-term HIIT, further enhanced aerobic capacity. Thus, the chlorella-induced increase in cardiac function may further enhance aerobic capacity through HIIT.

Indexed as

ChlorellaExercise ToleranceHeartHigh-Intensity Interval TrainingAdultAnimalsCardiac OutputCross-Over StudiesDouble-Blind MethodHeart RateHumansMaleOxygen ConsumptionRatsStroke VolumeYoung Adultexercisemaximal oxygen uptakemicroalgaestroke volume

Identifiers

PMID40871685
PMCPMC12389218

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.