Evidence mapPaperPMID 40871725Full record

ReviewNutrients2025

Integrating Precision Medicine and Digital Health in Personalized Weight Management: The Central Role of Nutrition.

Xiaoguang Liu, Miaomiao Xu, Huiguo Wang, Lin Zhu

Abstract readReview
In one paragraph

Review in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoguang LiuCollege of Sports and Health, Guangzhou Sport University, Guangzhou 510500, China.ORCID 0000-0003-0183-2100
Miaomiao XuCollege of Physical Education, Guangdong University of Education, Guangzhou 510800, China.ORCID 0000-0003-1000-290X
Huiguo WangCollege of Sports and Health, Guangzhou Sport University, Guangzhou 510500, China.
Lin ZhuCollege of Sports and Health, Guangzhou Sport University, Guangzhou 510500, China.

Funding

Guangdong Provincial Sports Bureau 2024-2025 Science and Technology Innovation and Sports Culture Development Research Project GDSS2024N010National Natural Science Foundation of China 32300964
6 · The paper itself

Abstract

Obesity is a global health challenge marked by substantial inter-individual differences in responses to dietary and lifestyle interventions. Traditional weight loss strategies often overlook critical biological variations in genetics, metabolic profiles, and gut microbiota composition, contributing to poor adherence and variable outcomes. Our primary aim is to identify key biological and behavioral effectors relevant to precision medicine for weight control, with a particular focus on nutrition, while also discussing their current and potential integration into digital health platforms. Thus, this review aligns more closely with the identification of influential factors within precision medicine (e.g., genetic, metabolic, and microbiome factors) but also explores how these factors are currently integrated into digital health tools. We synthesize recent advances in nutrigenomics, nutritional metabolomics, and microbiome-informed nutrition, highlighting how tailored dietary strategies-such as high-protein, low-glycemic, polyphenol-enriched, and fiber-based diets-can be aligned with specific genetic variants (e.g., FTO and MC4R), metabolic phenotypes (e.g., insulin resistance), and gut microbiota profiles (e.g.,

Indexed as

Nutritional StatusObesityPrecision MedicineDigital HealthGastrointestinal MicrobiomeHumansNutrigenomicsTelemedicineWeight Lossdigital healthmetabolomicsmicrobiomenutrigenomicsobesityomics integrationpersonalized dietprecision nutrition

Identifiers

PMID40871725
PMCPMC12389408

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.