Evidence map›Paper›PMID 40872783›Full record

ReviewViruses2025

Hepatitis C Virus: Epidemiological Challenges and Global Strategies for Elimination.

Daniela Toma, Lucreția Anghel, Diana Patraș, Anamaria Ciubară

Abstract readReview
In one paragraph

Review in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniela TomaDoctoral School of Biomedical Sciences, "Dunarea de Jos" University Galati, 800008 Galati, Romania.ORCID 0009-0007-1474-0156
Lucreția AnghelSaint Apostle Andrew Emergency County Clinical Hospital, 177 Brailei St., 800578 Galati, Romania.
Diana PatrașDoctoral School of Biomedical Sciences, "Dunarea de Jos" University Galati, 800008 Galati, Romania.
Anamaria CiubarăFaculty of Medicine and Pharmacy, "Dunarea de Jos" University of Galati, 35 AI Cuza St., 800010 Galati, Romania.ORCID 0000-0003-0740-3702

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global elimination of hepatitis C virus (HCV) has been prioritized by the World Health Organization (WHO) as a key public health target, with a deadline set for 2030. This initiative aims to significantly reduce both new infection rates and HCV-associated mortality. A major breakthrough in achieving this goal has been the development of direct-acting antiviral agents (DAAs), which offer cure rates exceeding 95%, along with excellent safety and tolerability. Nevertheless, transmission via parenteral routes continues to be the dominant pathway, particularly among high-risk groups, such as individuals who inject drugs, incarcerated populations, those exposed to unsafe medical practices, and healthcare professionals. Identifying, monitoring, and delivering tailored interventions to these groups is crucial to interrupt ongoing transmission and to reduce the burden of chronic liver disease. On a global scale, several nations have demonstrated measurable progress toward HCV elimination, with some nearing the targets set by WHO. These achievements have largely resulted from context-adapted policies that enhanced diagnostic and therapeutic access while emphasizing outreach to vulnerable communities. This review synthesizes current advancements in HCV prevention and control and proposes strategic frameworks to expedite global elimination efforts.

Indexed as

Disease EradicationHepacivirusHepatitis CAntiviral AgentsGlobal HealthHumansWorld Health OrganizationAntiviral Agentsearly detectionepidemiologyhepatitis C virusinfection managementmodes of transmissionvulnerable populations

Identifiers

PMID40872783
PMCPMC12390683

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.