Evidence mapPaperPMID 40872813Full record

ReviewViruses2025

Breathless Aftermath: Post-COVID-19 Pulmonary Fibrosis.

Dharanya Muthiah, Kishore Vaddadi, Lin Liu

Abstract readReview
In one paragraph

Review in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. COVID-19, the disease that changed the world.Medicine and pharmacy reports · 2026
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dharanya MuthiahOklahoma Center for Respiratory and Infectious Diseases, Oklahoma State University, Stillwater, OK 74074, USA.ORCID 0009-0003-3752-7623
Kishore VaddadiOklahoma Center for Respiratory and Infectious Diseases, Oklahoma State University, Stillwater, OK 74074, USA.ORCID 0000-0003-0320-9064
Lin LiuOklahoma Center for Respiratory and Infectious Diseases, Oklahoma State University, Stillwater, OK 74074, USA.ORCID 0000-0002-4811-4897

Funding

Pilot Project Grant ProgramP30GM149368 · NIGMS · OKLAHOMA STATE UNIVERSITY STILLWATER · PI LIN LIU · 2023 to 2026
$5.5M
The Role of Iron In Pulmonary FibrosisR01HL157450 · NHLBI · OKLAHOMA STATE UNIVERSITY STILLWATER · PI LIN LIU · 2023 to 2026
$2.0M
A synthetic miR-7702: a potential therapeutic approach for SARS-CoV-2 infectionR21AI189861 · NIAID · OKLAHOMA STATE UNIVERSITY STILLWATER · PI LIU, LIN · 2025 to 2025
$411k
National Institutes of Health grants, Oklahoma Center for Adult Stem Cell Research and the Lundberg-Kienlen Endowment fund (to LL) R01HL157450, R21AI189861 and P30GM149368NHLBI NIH HHS R01 HL157450NIAID NIH HHS R21 AI189861NIGMS NIH HHS P30 GM149368
6 · The paper itself

Abstract

A significant number of individuals recovering from COVID-19 continue to experience persistent symptoms, collectively referred to as Post-Acute Sequelae of SARS-CoV-2 infection (PASC), or long COVID. Among these complications, post-COVID-19 pulmonary fibrosis (PC19-PF) is one of the most severe long-term outcomes, characterized by progressive lung scarring, chronic respiratory impairment, and reduced quality of life. Despite the increasing prevalence of PC19-PF, its underlying mechanisms remain poorly understood. In this review, we provide a comprehensive overview of PC19-PF, including its epidemiology, clinical manifestations, diagnostic strategies, and mechanistic insights. Additionally, we highlight the shared pathways between PC19-PF and other fibrotic lung diseases and discuss emerging therapeutic strategies. This review consolidates emerging insights from both clinical and experimental studies to advance our understanding of PC19-PF pathogenesis and guide the development of mechanism-based therapeutic approaches.

Indexed as

COVID-19Pulmonary FibrosisHumansLungPost-Acute COVID-19 SyndromeQuality of LifeSARS-CoV-2biomarkerinflammationlong COVIDpulmonary fibrosis

Identifiers

PMID40872813
PMCPMC12390685

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.