Article3 Biotech2025
Topical application of phycocyanin accelerates wound healing in STZ-induced diabetic rats via activation of the Nrf2 signaling pathway.
Article in 3 Biotech, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Phenylboronic acid modified AgRSC advances · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study aimed to evaluate the wound healing potential of phycocyanin (PC) in diabetic rats. STZ (55 mg/kg) was injected intraperitoneally in Wistar rats for the induction of diabetes. A sterile biopsy punch created a foot ulcer (5 mm). Diabetic rats were treated with topical PC (1.5% and 2.5%) for 2 weeks. Body weight and metabolic parameters were measured. Various biochemical estimations, including oxidative stress markers (LPO, PCO), antioxidant indices (GSH, SOD), collagen content, and anti-inflammatory markers (IL-1β, TNF-α, NF-κβ, IL-6), along with MMP-9, VEGF, Nrf2, and HO-1 levels were assessed in the wound tissue. MTT and in-vitro scratch assays were also performed. The results revealed that
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