Evidence map›Paper›PMID 40873549›Full record

ReviewFrontiers in pharmacology2025

Role of pharmacogenomics for prevention of hypersensitivity reactions induced by aromatic antiseizure medications.

Angel T Alvarado, Amparo Iris Zavaleta, César Li-Amenero, María R Bendezú, Jorge A Garcia, Haydee Chávez, Juan J Palomino-Jhong, Felipe Surco-Laos, Doris Laos-Anchante, Elizabeth J Melgar-Merino and 2 more

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Association BetweenPharmaceuticals (Basel, Switzerland) · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Angel T AlvaradoResearch Unit in Molecular Pharmacology and 4P Medicine, VRI, San Ignacio de Loyola University, Lima, Peru.
Amparo Iris ZavaletaMolecular Biology Laboratory, Faculty of Pharmacy and Biochemistry, National University of San Marcos, Lima, Peru.
César Li-AmeneroVictor Larco Herrera Hospital, Lima, Peru.
María R BendezúFaculty of Pharmacy and Biochemistry, San Luis Gonzaga National University of Ica, Ica, Peru.
Jorge A GarciaFaculty of Pharmacy and Biochemistry, San Luis Gonzaga National University of Ica, Ica, Peru.
Haydee ChávezFaculty of Pharmacy and Biochemistry, San Luis Gonzaga National University of Ica, Ica, Peru.
Juan J Palomino-JhongFaculty of Pharmacy and Biochemistry, San Luis Gonzaga National University of Ica, Ica, Peru.
Felipe Surco-LaosFaculty of Pharmacy and Biochemistry, San Luis Gonzaga National University of Ica, Ica, Peru.
Doris Laos-AnchanteFaculty of Pharmacy and Biochemistry, San Luis Gonzaga National University of Ica, Ica, Peru.
Elizabeth J Melgar-MerinoFaculty of Pharmacy and Biochemistry, San Luis Gonzaga National University of Ica, Ica, Peru.
Pompeyo A Cuba-GarciaFaculty of Pharmacy and Biochemistry, San Luis Gonzaga National University of Ica, Ica, Peru.
Paulina E Yarasca-CarlosBiological Sciences Faculty, San Luis Gonzaga National University of Ica, Ica, Peru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epilepsy is the second most common neurological condition worldwide, characterized by recurrent, unprovoked, self-limiting seizures of genetic, acquired, or unknown origin. The objective was to describe the pharmacogenomic markers associated with hypersensitivity reactions induced by aromatic antiseizure medications. This review explored the pharmacokinetics, pharmacogenomics of

Indexed as

antiseizure medicationsclinical implicationsepilepsyhypersensitivity reactionspharmacogenomics

Identifiers

PMID40873549
PMCPMC12378293

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.