Evidence map›Paper›PMID 40873970›Full record

ReviewFood science & nutrition2025

Aromatic Volatile Compounds of Essential Oils: Distribution, Chemical Perspective, Biological Activity, and Clinical Applications.

Hamdoon A Mohammed, Ghassan M Sulaiman, Ali Z Al-Saffar, Mayyadah H Mohsin, Riaz A Khan, Noora A Hadi, Shahad Basil Ismael, Fatma Elshibani, Ahmed Ismail, Mosleh M Abomughaid

Abstract readReview
In one paragraph

Review in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Pickering Emulsion Stabilized by Chitosan-ModifiedPharmaceuticals (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hamdoon A MohammedDepartment of Medicinal Chemistry and Pharmacognosy College of Pharmacy, Qassim University Buraydah Saudi Arabia.
Ghassan M SulaimanCollege of Applied Sciences University of Technology Baghdad Iraq.ORCID https://orcid.org/0000-0001-6388-3849
Ali Z Al-SaffarDepartment of Molecular and Medical Biotechnology College of Biotechnology, Al-Nahrain University Baghdad Iraq.
Mayyadah H MohsinCollege of Applied Sciences University of Technology Baghdad Iraq.
Riaz A KhanDepartment of Medicinal Chemistry and Pharmacognosy College of Pharmacy, Qassim University Buraydah Saudi Arabia.
Noora A HadiDepartment of Plant Biotechnology, College of Biotechnology Al-Nahrain University Baghdad Iraq.
Shahad Basil IsmaelDepartment of Molecular and Medical Biotechnology College of Biotechnology, Al-Nahrain University Baghdad Iraq.
Fatma ElshibaniDepartment of Pharmacognosy Faculty of Pharmacy, University of Benghazi Benghazi Libya.
Ahmed IsmailPharmacognosy Department Faculty of Pharmacy, Fayoum University Fayoum Egypt.
Mosleh M AbomughaidDepartment of Medical Laboratory Sciences College of Applied Medical Sciences, University of Bisha Bisha Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Volatile, or essential, oils are the principal odorous components of certain plant species and constitute aliphatic and aromatic compounds in the oils' natural mix. The aromatic compounds are present in significant proportions in the oils of several plant species, usually referred to as aromatic plants, and hence the aromatic essential oils. These aromatic classes of compounds are abundant in oils of cloves, thyme, wintergreen, etc. The aromatic volatile compounds of essential oils (ACEO) are used in the treatment of several disorders, including infection, inflammation, irritable bowel syndrome (IBS), and as antihelminthics, among others. The ACEO are used in confectionary, beauty products, food, pharmaceuticals, and other medicaments. A plentiful number of over-the-counter (OTC) products are also prepared by ACEO and are abundantly distributed in the market. The present review deliberates on the origins, biogenesis, chemical structures, and bioactivities of the ingrained aromatic constituents of the essential oils sourced from different plant species. The review also highlights the importance of ACEO in modern food, cosmetics, and pharmaceutical industries. An overview of the clinical trials of the aromatic constituents and their applications in aromatherapy domains is also outlined. The review addresses a gap in the current literature concerning the aromatic components of essential oils by utilizing prior reviews and research articles. This review serves as a comprehensive source, detailing the chemistry, bioactivity, and therapeutic applications of the aromatic constituents of essential oils, along with their uses in both traditional and contemporary medicine, as well as the mechanistic aspects of the biological activity of these constituents derived from various plant-sourced essential oils.

Indexed as

aromatic volatile compounds of essential oils (ACEO)biogenesisbiological activitychemistryclinical applicationsessential oil

Identifiers

PMID40873970
PMCPMC12378133

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.