ArticleTheScientificWorldJournal2025
Heavy Metals in Cannabis Vapes and Their Health Implications-A Scoping Review.
Article in TheScientificWorldJournal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cannabis vaping involves the vaporization of cannabis vape (CV) liquid via a vape pen made of metallic and nonmetallic parts. Recently, various metal contaminants that originate from cannabis, as well as the vape liquid packaging device, were reported in CV liquids and aerosols. Heavy metal exposure from CVs is associated with various health afflictions and should be regulated. This scoping review intends to investigate the literature on heavy metal releases from CVs and their impact on health. This review was conducted according to the PRISMA-ScR scoping review guidelines. Initial search in electronic databases such as Medline (PubMed), Scopus, Embase, and Web of Science yielded nine studies published until February 2024. The metals released from CVs, the variables influencing their leaching, and any documented adverse health impacts were recorded. Findings revealed that the structural elements of the CVs leached metals such as nickel (Ni), chromium (Cr), lead (Pb), cobalt (Co), cadmium (Cd), and copper (Cu), which were transported into the aerosol as tiny particles. Several factors, including the structural integrity of the device components, device age, operating temperature, vape liquid pH, and viscosity cutting agents in the vape liquid, caused metal dissolution. Even though none of the studies evaluated the direct health impact of these metals, they proposed that they may affect multiple body organs, specifically the lungs, where they were associated with electronic vaping device use-associated lung injury (EVALI). These metals might expedite the transformation of vitamin E acetate into ketenes, which are associated with EVALI. We can conclude that heavy metals beyond the regulatory guidelines are released from CVs and have negative health consequences. Further research is required to improve the CV design elements to lower the metal leaching. Additionally, disclosing the CV packaging contents to consumers is essential to prevent possible health risks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.