ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2026
67 national-level factors potentially related to the incidence of kidney replacement therapy across Europe.
Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Over 500 000 people on kidney replacement therapy in the European Union.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026Review
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Authors and funding
6 authors.
Funding
Abstract
backgroundKidney replacement therapy (KRT) incidence varies considerably across European countries. We aimed to provide an overview of factors potentially related to KRT incidence for all individual European countries and across low, middle and high KRT incidence countries and to describe the relationship between these factors and KRT incidence.
methodsWe obtained unadjusted KRT incidence rates from the European Renal Association (ERA) Registry annual reports and studies. Countries were divided into low [0-100 per million population (pmp)], middle (100-200 pmp) and high (>200 pmp) KRT incidence countries. Online sources were searched for information on factors potentially related to KRT incidence including geographic, socioeconomic, sociocultural and health-related factors, and factors related to chronic kidney disease (CKD) and national capacity for CKD prevention. Univariate linear or polynomial regression were used to examine whether factors and KRT incidence were related, with the R coefficient as metric of correlation strength. Significant factors were also evaluated separately in less affluent and wealthy countries.
resultsThirty-eight European countries were included, and divided into 12 low, 21 middle and 5 high KRT incidence countries. Among 67 factors evaluated, the number of practicing physicians (R = 0.374, P = .023), the population density (R = 0.508, P = .001), the median age at KRT initiation (R = 0.549, P = .001), the percentages of CKD-attributed deaths (R = 0.418, P = .038) and disability-adjusted life years (R = 0.420, P = .010), and the physical inactivity prevalence (R = 0.569, P < .001) were significantly positively correlated with KRT incidence. These findings were consistent among less affluent countries, while median age at KRT initiation was the only significant factor among wealthy countries (R = 0.889, P < .001). After multiple testing correction, median age at KRT initiation, physical inactivity prevalence and population density remained correlated with KRT incidence.
conclusionsThese findings may be a first step for policy makers, stakeholders and nephrologists to optimize healthcare (planning) regarding KRT initiation and reduce KRT incidence disparities.
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