Evidence map›Paper›PMID 40874964›Full record

ArticleArchives of orthopaedic and trauma surgery2025

High retention rates of custom 3D printed titanium implants in complex pelvic reconstruction, a report on 106 consecutive cases over 10 years.

Richard Boyle, Corey Scholes, Daniel Franks, Amish Lodhia, Meredith Harrison-Brown, Milad Ebrahimi, Maurice Guzman, Paul Stalley

Abstract read
In one paragraph

Article in Archives of orthopaedic and trauma surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Richard BoyleSydney University, Camperdown, Australia. rich_boyle@hotmail.com.
Corey ScholesEBM Analytics, Sydney, Australia. cscholes@ebma.com.au.
Daniel FranksSydney University, Camperdown, Australia.
Amish LodhiaRoyal Prince Alfred Hospital, Camperdown, Australia.
Meredith Harrison-BrownEBM Analytics, Sydney, Australia.
Milad EbrahimiEBM Analytics, Sydney, Australia.
Maurice GuzmanSydney University, Camperdown, Australia.
Paul StalleySydney University, Camperdown, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAccess to custom 3D printed pelvic implants (3DPI) is improving for application in both arthroplasty revision and tumour reconstruction. There is limited evidence regarding the safety and outcomes of such implants for large bony defects of the pelvis. The aim of this study is to report the incidence of complications, patient mortality and implant survival following pelvic reconstruction using custom 3Dprinted prostheses in the setting of extensive pelvic bone defects following pelvic tumour resection or failure of total hip arthroplasty (THA). MATERIALS AND

methodsPatients who underwent reconstruction with a custom 3D printed pelvic prosthesis (3DPI) were identified from our clinical outcomes registry (Complex Reconstruction and Sarcoma Surgical Outcomes Registry; ANZCTRN 12621001421820). Indications for surgery, adverse events, reoperations and rates and modes of failure were recorded. Kaplan-Meier and multistate survival curves were generated for cumulative survival based on indication.

resultsOne hundred and six procedures were completed (Revision THA = 33; Tumour Pelvis = 73) with a median follow up of 4.1 years, ranging from 0.6 to 10 years. Acetabular loosening was the most frequent indication for the Revision THA cohort, while indications for tumour varied across primary presentations, metastases and failures of previous resection/reconstruction. Intraoperative complications were observed in 4.1% (95%CI 1.1-12.3) of Tumour Pelvis cases. Overall implant retention was 96% (90-99). No mortality events were observed in the Revision THA cohort, with 5-year patient survival 79% (70-90) in the Tumour Pelvis cohort. Procedure-survival free from periprosthetic infection was 86% (74-100) in the Revision THA cohort and 85% (76-95) in the Tumour Pelvis cohort. Modelling adverse events using multistate survival models in both cohorts revealed complex time-varying presentation of adverse events, with a significant burden of reoperations and local tumour recurrence in the Tumour Pelvis cohort.

conclusions3DPIs are a safe and viable option for complex reconstruction of the pelvis across a range of oncological and non-oncological indications. The initial results of the present study provide important information to aid in counselling patients about such procedures and allocating healthcare resources for ongoing care. Further work is required to document functional and biomechanical outcomes in these patient populations.

trial registrationAustralian New Zealand Clinical Trials Registry (ANZCTRN 12621001421820); Registration date 21-Oct-2021.

Indexed as

Arthroplasty, Replacement, HipBone NeoplasmsHip ProsthesisPelvic BonesPlastic Surgery ProceduresPrinting, Three-DimensionalProsthesis DesignAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPostoperative ComplicationsProsthesis FailureTitaniumClinical outcomesClinical registryComplex pelvic reconstructionCustom 3D printed pelvic implants

Identifiers

PMID40874964
PMCPMC12394299

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.