Article in Biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
14 authors.
Olivia M PeduzziDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0002-6867-4955
Gavin M PalowitchDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0003-0283-7894
John P GajewskiDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Kai HuDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Alyssa WheelerDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Tatiana N LaremoreHuck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Steve SillettiDepartment of Chemistry & Biochemistry, University of California San Diego, La Jolla, California 92093, United States.
Elizabeth A KomivesDepartment of Chemistry & Biochemistry, University of California San Diego, La Jolla, California 92093, United States.ORCID 0000-0001-5264-3866
Benjamin D AllenDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0001-6914-5572
Alexey SilakovDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Carsten KrebsDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
J Martin BollingerDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0003-0751-8585
Chi-Yun LinDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0001-6555-8767
Amie K BoalDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0002-1234-8472
Funding
A Synchrotron Radiation Structural Biology ResourcesP30GM133894 · NIGMS · STANFORD UNIVERSITY · PI Aina E. Cohen, KEITH O HODGSON · 2020 to 2026
$43.3M
User Training & OutreachP30GM138396 · NIGMS · UCHICAGO ARGONNE, LLC · PI ROBERT F. FISCHETTI, JANET L. SMITH · 2020 to 2026
$34.3M
Mapping the Structural Basis for Mechanistic Diversity in Metalloenzyme SuperfamiliesR35GM119707 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI Amie K Boal · 2016 to 2026
$5.0M
Mechanisms of Mononuclear non-Heme-Iron EnzymesR35GM127079 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI CARSTEN KREBS · 2018 to 2026
$3.8M
High-Speed High-Sensitivity Detector for X-ray Micro-Crystallography at GM/CA@APSS10OD012289 · OD · UNIVERSITY OF CHICAGO · PI FISCHETTI, ROBERT F. · 2014 to 2014
$2.0M
Diverse Transition-Metal and Free-Radical Chemistry Enabling 2'-Deoxyribonucleotide Production by Bacteria in Restrictive EnvironmentsR01GM132653 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI BOLLINGER, JOSEPH M · 2019 to 2022
$1.6M
The role of geometric structure in avoidance of oxygen rebound to enable aliphatic halogenation and oxacyclization by non-heme Fe(IV)-oxo (ferryl) complexesR01GM141284 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI SILAKOV, ALEXEY · 2022 to 2025
$1.5M
Synapt G2-S System with HXMS AutomationS10OD016234 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KOMIVES, ELIZABETH A. · 2013 to 2013
Ribonucleotide reductases (RNRs) generate 2'-deoxynucleotides for DNA biosynthesis, a reaction essential to all life. Class I RNRs have two subunits, α and β. α binds and reduces the substrate, whereas β oxidizes one of the cysteines in α to a C3'-H-bond-cleaving thiyl radical to begin the reaction. The α-Cys oxidant in β is variously a tyrosyl radical (Y
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.