ArticleNature communications2025
Chelation-based iron uptake mitigates the effects of prolonged high-temperature stress in cool-season grasses.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Accelerating iron biofortification in millets: progress, challenges, and future prospects.Planta · 2026Review
- Machine learning-guided multi-omics suggests iron-dependent hormonal signaling drives root morphological plasticity in wheat under temperature stress.The New phytologist · 2026Article
- Mineral elements-mediated responses govern cadmium accumulation in plants under C14 alkane stress.Frontiers in microbiology · 2026Article
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Authors and funding
19 authors.
Funding
Abstract
High-temperature stress poses a significant threat to agricultural productivity and ecological diversity. Here, we show the effects of prolonged high-temperature stress on wheat (Triticum aestivum) and the model grass Brachypodium distachyon and demonstrate that heat stress induces iron deficiency in newly emerged leaves. Quantitative trait locus analysis of B. distachyon reveals a genomic region associated with heat resilience that includes the transporter of mugineic acid family phytosiderophores 1 gene (BdTOM1). Iron-deficiency-related genes including BdTOM1 are more highly expressed in a high-temperature-tolerant B. distachyon accession at high temperature than in a sensitive accession, resulting in greater secretion of deoxymugineic acid. Treatment with proline-2'-deoxymugineic acid mitigates heat-induced growth inhibition, but excess iron treatment leads to toxicity in both species. Our findings highlight the role of heat-induced nutritional stress in prolonged high-temperature stress and suggest that iron homeostasis could provide a promising target for improving crop resilience to climate extremes.
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Registered trials
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