Evidence map›Paper›PMID 40877470›Full record

SynthesisMolecular psychiatry2026

Prevalence of attention deficit hyperactivity disorder/hyperkinetic disorder of pediatric and adult populations in clinical settings: a systematic review, meta-analysis and meta-regression.

Simon Johnson, Eric Lim, Peter Jacoby, Stephen V Faraone, Benjamin Minche Su, Marco Solmi, Benjamin Forrest, Bethany Furfaro, Kiri von Klier, Jenny Downs and 1 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Molecular psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Simon JohnsonNorth Metropolitan Health Service, Perth, WA, Australia.ORCID 0000-0002-4126-7014
Eric LimSchool of Nursing, Murdoch University, Murdoch,, Perth, WA, Australia.ORCID 0000-0003-4860-9336
Peter JacobyTelethon Kids Institute, Perth, WA, Australia.
Stephen V FaraoneDepartment of Psychiatry, Norton College of Medicine at SUNY Upstate Medical University, Syracuse, NY, USA.ORCID 0000-0002-9217-3982
Benjamin Minche SuEast Metropolitan Health Service, Perth, WA, Australia.ORCID 0009-0001-6646-9720
Marco SolmiSCIENCES lab, Department of Psychiatry, University of Ottawa, Ottawa, ON, Canada.ORCID 0000-0003-4877-7233
Benjamin ForrestArmadale Mental Health Services, Perth, WA, Australia.
Bethany FurfaroRoyal Perth Hospital, Perth, WA, Australia.
Kiri von KlierYouth Mental Health, Fiona Stanley Hospital, Murdoch, Perth, WA, Australia.ORCID 0009-0006-9370-5967
Jenny Downs *Telethon Kids Institute, Perth, WA, Australia.ORCID 0000-0001-7358-9037
Wai Chen *Youth Mental Health, Fiona Stanley Hospital, Murdoch, Perth, WA, Australia. wai.chen@curtin.edu.au.ORCID 0000-0002-0477-7883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAttention-Deficit/Hyperactivity Disorder (ADHD)/Hyperkinetic Disorder (HD) is linked to increased risks of morbidity, comorbidity and mortality, with higher prevalence in clinical populations. The differential prevalence of ADHD/HD across adult and pediatric clinical populations, influenced by factors such as time trends, sex, age, geographic regions, and comorbidities, has not been systematically assessed.

methodsMEDLINE, CINAHL, Embase and PsycINFO databases were searched from inception to 1st August 2023 for eligible full-text papers published in English, and reviewing reference lists of identified studies and review papers. Studies reporting ADHD/HD prevalence in adult and pediatric clinical populations were included. Meta-regression evaluated the effects of geographic region, year of publication and sample size.

resultsFrom 30,740 citations, we reviewed 521 full-text articles, yielding 311 studies for inclusion (including 653,558 pediatric and 43,311 adult participants). Overall, worldwide pooled prevalence of ADHD/HD in clinical settings for pediatrics was 32.4% (95% CI 31-34%), and in adults 21.4% (95% CI 20-23%). Prevalence was higher in outpatient settings than inpatient settings. Prevalence based on rating scales was higher than studies using diagnostic interviews or clinical record review. Prevalence varied significantly across subspecialist settings for children and adults. No significant time trend was detected between 1981-2023. Pediatric prevalence appears influenced by geographic region but not year of publication or sample size. For adults, larger sample sizes were associated with lower prevalence estimates.

conclusionsADHD/HD prevalence in clinical populations is 8-9-fold higher than community estimates. With these patients at risk for many adverse outcomes, our findings underscore the critical importance of resource allocation for screening, diagnosing and treatment.

Indexed as

Attention Deficit Disorder with HyperactivityAdolescentAdultChildComorbidityFemaleHumansMalePrevalence

Identifiers

PMID40877470
PMCPMC12700782

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.