SynthesisBMC gastroenterology2025
Effect of magnetically guided capsule endoscopy on gastrointestinal transit time and diagnostic yield: a systematic review and meta-analysis.
Synthesis in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Effect of Multiple Pharmacological Interventions and Magnetic Control on Capsule Endoscopy Gastrointestinal Transit Time and Diagnostic Yield: A Systematic Review and Meta-Analysis.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCapsule endoscopy (CE) is a primary tool for small bowel visualization, but its diagnostic yield can be limited by prolonged transit times and finite battery life. Various interventions, including prokinetics, purgatives, and magnetic steering, are used to optimize CE performance. This systematic review and meta-analysis compare the effectiveness of these strategies in improving transit times and completion rates.
methodsA systematic search of PubMed, Web of Science, and Scopus was conducted for randomized controlled trials and observational studies evaluating magnetic control, prokinetics, or purgatives in adult patients undergoing small bowel CE. Primary outcomes were gastric transit time (GTT), small bowel transit time (SBTT), and completion rate (CR). A random-effects model was used for all meta-analyses.
resultsForty studies involving 3,041 participants were included. For reducing GTT, Among the included studies, erythromycin and magnetic control were each associated with shorter gastric transit times, while lubiprostone and PEG showed beneficial effects on small bowel transit-relative to their respective controls. Metoclopramide and castor oil were most strongly associated with an increased completion rate.
conclusionsNo single intervention optimizes all CE parameters. Erythromycin and magnetic control are effective for rapid gastric transit, while lubiprostone and PEG expedite small bowel transit. To maximize the likelihood of a complete examination, metoclopramide is a well-supported option. These findings allow clinicians to select a tailored pre-procedural strategy based on the specific goals of the CE examination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.