Evidence map›Paper›PMID 40877957›Full record

ArticleRadiation oncology (London, England)2025

Nasopharyngeal cancer adaptive radiotherapy with CBCT-derived synthetic CT: deep learning-based auto-segmentation precision and dose calculation consistency on a C-Arm linac.

Weijie Lei, Lixiang Han, Zhenmei Cao, Tingting Duan, Bin Wang, Caihong Li, Xi Pei

Abstract read
In one paragraph

Article in Radiation oncology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Weijie LeiDepartment of Radiation Oncology, Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, China. weijie_lei@163.com.
Lixiang HanDepartment of Radiation Oncology, Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Zhenmei CaoDepartment of Radiation Oncology, Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Tingting DuanDepartment of Radiation Oncology, Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Bin WangDepartment of Radiation Oncology, Xuzhou First People's Hospital, Xuzhou, China.
Caihong LiDepartment of Radiation Oncology, Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Xi PeiTechnology Development Department, Anhui Wisdom Technology Co.,Ltd, Hefei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the precision of automated segmentation facilitated by deep learning (DL) and dose calculation in adaptive radiotherapy (ART) for nasopharyngeal cancer (NPC), leveraging synthetic CT (sCT) images derived from cone-beam CT (CBCT) scans on a conventional C-arm linac. MATERIALS AND

methodsSixteen NPC patients undergoing a two-phase offline ART were analyzed retrospectively. The initial (pCT

resultsMost anatomical structures demonstrated high pCT-sCT agreement, with mean values of DSC > 0.85 and HD

conclusionThe proposed method exhibited minor variations in volumetric and dosimetric parameters compared to prior treatment data, suggesting potential efficiency improvements for ART in NPC through reduced human dependency.

Indexed as

Cone-Beam Computed TomographyDeep LearningNasopharyngeal NeoplasmsParticle AcceleratorsRadiotherapy, Image-GuidedRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedAdultFemaleHumansMaleMiddle AgedRadiotherapy DosageRetrospective StudiesAdaptive radiotherapyAutomated segmentationDeep learningNasopharyngeal cancerSynthetic CT

Identifiers

PMID40877957
PMCPMC12395649

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.