Evidence map›Paper›PMID 40878170›Full record

ReviewBiomaterials science2025

Revisiting the biophysical aspects of extracellular-matrix-mimicking hydrogels: what cells see

Jingchao Sui, Sarah Pragnere, Nicholas A Kurniawan

Abstract readReview
In one paragraph

Review in Biomaterials science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Beyond labeling: differential AcRegenerative biomaterials · 2026
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jingchao SuiDepartment of Biomedical Engineering, Eindhoven University of Technology, PO Box 513, 5600 MB, Eindhoven, the Netherlands. kurniawan@tue.nl.ORCID http://orcid.org/0000-0001-7883-3844
Sarah PragnereDepartment of Biomedical Engineering, Eindhoven University of Technology, PO Box 513, 5600 MB, Eindhoven, the Netherlands. kurniawan@tue.nl.ORCID http://orcid.org/0000-0003-2775-3582
Nicholas A KurniawanDepartment of Biomedical Engineering, Eindhoven University of Technology, PO Box 513, 5600 MB, Eindhoven, the Netherlands. kurniawan@tue.nl.ORCID http://orcid.org/0000-0003-0473-0222

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The extracellular matrix (ECM) is critical in regulating cell behavior and tissue function. This recognition has driven the development of ECM surrogates to better understand cell-ECM interactions and advance biomedical applications. Hydrogels are promising candidates for this purpose due to their biocompatibility, tunability, and ability to embed cells in 3D environments. While early efforts in the design of ECM-mimicking hydrogels focused on macromolecular type, it is now clear that their biophysical parameters, such as polymer molecular weight, fibrous

Indexed as

Cell Culture Techniques, Three DimensionalCellular MicroenvironmentExtracellular MatrixHydrogelsAnimalsElastic ModulusHumansMechanotransduction, CellularHydrogels

Identifiers

PMID40878170
PMCPMC12394797

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.