Evidence map›Paper›PMID 40878355›Full record

ReviewMolecular pain

Analgesia and silymarin: What are the opportunities and challenges?

Mehdi Dehghani Firoozabadi, Behrang Nooralishahi, Fatemeh Rezaei-Tazangi

Abstract readReview
In one paragraph

Review in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mehdi Dehghani FiroozabadiTehran Heart Center, Cardiovascular Diseases Research Institute, Anesthesiology, Critical Care and Pain Research Center, Tehran University of Medical Science, Tehran, Iran.
Behrang NooralishahiTehran Heart Center, Cardiovascular Diseases Research Institute, Anesthesiology, Critical Care and Pain Research Center, Tehran University of Medical Science, Tehran, Iran.ORCID 0000-0003-1550-153X
Fatemeh Rezaei-TazangiDepartment of Anatomy, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.ORCID 0000-0003-1402-6482

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pain is an unpleasant sensory and emotional sensation about actual or possible tissue damage that can cause remarkable health and economic problems. For pain relief, analgesic drugs are commonly utilized; however, their prolonged use can cause different side effects from mild to severe stages. Therefore, discovering new and alternative choices for analgesic purposes is of importance. Hopeful evidence has shown that flavonoid compounds have various therapeutic and pharmacological potentials. Among these, silymarin, obtained from the milk thistle plant

Indexed as

AnalgesiaAnalgesicsPainSilymarinAnimalsHumansAnalgesicsSilymarinanalgesiaantinociceptiveSilymarin

Identifiers

PMID40878355
PMCPMC12464410

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.