Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Jiaying FuInstitute for Experimental Cardiovascular Medicine, University Heart Center Freiburg-Bad Krozingen, Medical Faculty and Medical Center-University of Freiburg Freiburg im Breisgau Germany.ORCID 0009-0001-4999-7249
Breanne A CameronInstitute for Experimental Cardiovascular Medicine, University Heart Center Freiburg-Bad Krozingen, Medical Faculty and Medical Center-University of Freiburg Freiburg im Breisgau Germany.ORCID 0000-0003-0334-1217
Patrick SchönleitnerDepartment of Physiology, Cardiovascular Research Institute Maastricht Maastricht University Maastricht Netherlands.
Teresa SchiattiInstitute for Experimental Cardiovascular Medicine, University Heart Center Freiburg-Bad Krozingen, Medical Faculty and Medical Center-University of Freiburg Freiburg im Breisgau Germany.ORCID 0009-0003-8857-733X
Marion KuiperDepartment of Physiology, Cardiovascular Research Institute Maastricht Maastricht University Maastricht Netherlands.
Ana Simon-ChicaSpanish National Center for Cardiovascular Research, Carlos III (CNIC) Madrid Spain.
Josef MadlInstitute for Experimental Cardiovascular Medicine, University Heart Center Freiburg-Bad Krozingen, Medical Faculty and Medical Center-University of Freiburg Freiburg im Breisgau Germany.ORCID 0000-0003-3637-2546
Clemens KreutzSignalling Research Centres BIOSS and CIBSS University of Freiburg Germany.ORCID 0000-0002-8796-5766
David Filgueiras-RamaSpanish National Center for Cardiovascular Research, Carlos III (CNIC) Madrid Spain.ORCID 0000-0001-5909-2454
Ulrich SchottenDepartment of Physiology, Cardiovascular Research Institute Maastricht Maastricht University Maastricht Netherlands.ORCID 0000-0003-1532-3315
Ursula RavensInstitute for Experimental Cardiovascular Medicine, University Heart Center Freiburg-Bad Krozingen, Medical Faculty and Medical Center-University of Freiburg Freiburg im Breisgau Germany.ORCID 0000-0003-3813-3127
Peter KohlInstitute for Experimental Cardiovascular Medicine, University Heart Center Freiburg-Bad Krozingen, Medical Faculty and Medical Center-University of Freiburg Freiburg im Breisgau Germany.ORCID 0000-0003-0416-6270
Eva A Rog-ZielinskaInstitute for Experimental Cardiovascular Medicine, University Heart Center Freiburg-Bad Krozingen, Medical Faculty and Medical Center-University of Freiburg Freiburg im Breisgau Germany.ORCID 0000-0002-3295-4728
Gudrun AntoonsDepartment of Physiology, Cardiovascular Research Institute Maastricht Maastricht University Maastricht Netherlands.ORCID 0000-0002-5846-0363
Rémi PeyronnetInstitute for Experimental Cardiovascular Medicine, University Heart Center Freiburg-Bad Krozingen, Medical Faculty and Medical Center-University of Freiburg Freiburg im Breisgau Germany.ORCID 0000-0002-5708-6410
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
backgroundMechanical stretch of the myocardium is proarrhythmic and alters cellular Ca
methodsFreshly isolated rabbit, pig, and human left atrial cardiomyocytes were stretched axially using glass microrods. Free cytosolic Ca
resultsDiastolic stretch provoked SiS, which was prevented by disrupting microtubules with colchicine, but unaffected by inhibition of NADPH oxidase 2 or scavenging of reactive oxygen species. SiS was absent in Na
conclusionsIn atrial cardiomyocytes, diastolic stretch enhances Ca
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Stretch-Induced Increase in Ca · full record | Socratic