Analysis of Inositol Phosphates, Diphosphoinositol Phosphates, and Their Analogs by HPLC on an Acid-Compatible Stationary Phase with Detection by Complexation with Ferric Ion.

Hayley L Whitfield, Colleen Sprigg, Andrew M Riley, Megan L Shipton, Barry V L Potter, Charles A Brearley

Abstract read

In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Hayley L WhitfieldSchool of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, UK.

Colleen SpriggSchool of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, UK.

Andrew M RileyMedicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Oxford, UK.

Megan L ShiptonMedicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Oxford, UK.

Barry V L PotterMedicinal Chemistry & Drug Discovery, Department of Pharmacology, University of Oxford, Oxford, UK.

Charles A BrearleySchool of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, UK. c.brearley@uea.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-performance anion-exchange chromatography with acid eluents allows for effective separation of myo-inositol tetrakisphosphates, myo-inositol pentakisphosphates, diphospho-myo-inositol phosphates (inositol pyrophosphates), inositol hexakisphosphates, inositol pyrophosphate analogs, and carbohydrate-based analogs of inositol phosphates. All are detectable by postcolumn addition of ferric ion. In the following, we provide examples drawn from characterization of ITPK, IPK1, and IP

Indexed as

Ferric CompoundsInositol PhosphatesChromatography, High Pressure LiquidChromatography, Ion ExchangeFerric CompoundsInositol PhosphatesDiphosphoinositol phosphatesFerric ionHPLCInositol phosphatesInositol pyrophosphates

Identifiers

PMID40879979

DOI10.1007/978-1-0716-4799-8_6

What Socratic holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.